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精神分裂谱系障碍患者的精神动力日治疗方案:治疗变化的动力和预测因素。

Psychodynamic day treatment programme for patients with schizophrenia spectrum disorders: Dynamics and predictors of therapeutic change.

机构信息

Center for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry and UHSL, First Faculty of Medicine, Charles University, Prague, Czech Republic.

Psychotherapeutic and Psychosomatic Clinic, ESET, Prague, Czech Republic.

出版信息

Psychol Psychother. 2018 Jun;91(2):157-168. doi: 10.1111/papt.12153. Epub 2017 Sep 13.

Abstract

OBJECTIVES

The purpose of this study was to test whether a psychodynamically based group psychotherapeutic programme might improve symptoms, social functions, or quality of life in patients with schizophrenia spectrum disorders and to investigate factors that might predict clinical improvement or dropouts from the programme.

DESIGN

A quantitative prospective cohort study.

METHODS

We have investigated 81 patients with schizophrenia spectrum disorders who participated in a 9-month psychodynamically based psychotherapeutic day programme. The patients were assessed at the beginning and end of the programme, and then at 1-year follow-up. The assessment included psychotic manifestations (HoNOS), quality of life (WHOQOL-BREF), demographic data, and daily doses of medication. 21 patients dropped out from the programme, and 46 patients succeeded in undergoing follow-up assessment.

RESULTS

The psychotic manifestations (self-rating version of HoNOS) and quality of life measured with WHOQOL-BREF (domains of social relationships and environment) were significantly improved at the end of the programme and at follow-up. However, the manifestations on the version for external evaluators of HoNOS were improved only at follow-up. Years of psychiatric treatment, number of hospitalizations or suicide attempts, and experience of relationships with a partner were negatively related to clinical improvement, whereas symptom severity, current working, or study activities were related positively.

CONCLUSIONS

The results show that a group psychodynamic programme may improve the clinical status and quality of life of patients with schizophrenia spectrum disorders. This type of programme is more beneficial for patients with higher pre-treatment symptom severity and the presence of working or study activities.

PRACTITIONER POINTS

A psychodynamically based group programme improves the clinical status and quality of life in patients with schizophrenia spectrum disorders. Data indicate that changes on the subjective level are detectable by the end of the programme, while changes on the objective level are detectable at follow-up assessment. Symptom severity and working or study activities are positively related to the clinical improvement in this type of programme, while a high number of years in psychiatric treatment or psychiatric hospitalizations are negatively related. The doses of medication (antipsychotics or antidepressants) show no significant relationship to clinical improvement.

摘要

目的

本研究旨在检验精神分析为基础的团体心理治疗方案是否可以改善精神分裂谱系障碍患者的症状、社会功能或生活质量,并探讨可能预测临床改善或退出该方案的因素。

设计

一项定量的前瞻性队列研究。

方法

我们调查了 81 名参加为期 9 个月的精神分析为基础的心理治疗日间方案的精神分裂谱系障碍患者。在方案开始和结束时以及 1 年随访时对患者进行评估。评估包括精神病表现(HoNOS)、生活质量(WHOQOL-BREF)、人口统计学数据和每日药物剂量。21 名患者退出了该方案,46 名患者成功完成了随访评估。

结果

精神病表现(HoNOS 的自评版本)和生活质量(WHOQOL-BREF 测量的社会关系和环境领域)在方案结束时和随访时显著改善。然而,HoNOS 的外部评估者版本的表现仅在随访时改善。精神病治疗年限、住院次数或自杀企图次数以及与伴侣关系的经历与临床改善呈负相关,而症状严重程度、当前工作或学习活动与临床改善呈正相关。

结论

结果表明,团体心理动力学方案可能改善精神分裂谱系障碍患者的临床状况和生活质量。这种类型的方案对治疗前症状严重程度较高且有工作或学习活动的患者更有益。

实践者要点

精神分析为基础的团体方案可改善精神分裂谱系障碍患者的临床状况和生活质量。数据表明,在方案结束时可检测到主观水平的变化,而在随访评估时可检测到客观水平的变化。在这种类型的方案中,症状严重程度和工作或学习活动与临床改善呈正相关,而精神病治疗年限或精神病住院次数较高则呈负相关。药物剂量(抗精神病药或抗抑郁药)与临床改善无显著关系。

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