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牙齿吸收不是遗传性的。

Tooth resorptions are not hereditary.

作者信息

Consolaro Alberto, Bianco Débora de Almeida

机构信息

Bauru School of Dentistry, Universidade de São Paulo (Bauru/SP, Brazil). Ribeirão Preto School of Dentistry, Universidade de São Paulo (Ribeirão Preto/SP, Brazil).

School of Dentistry, Universidade Estadual de Maringá (Maringá/PR, Brazil).

出版信息

Dental Press J Orthod. 2017 Jul-Aug;22(4):22-27. doi: 10.1590/2177-6709.22.4.022-027.oin.

Abstract

Root resorptions caused by orthodontic movement are not supported by consistent scientific evidence that correlate them with heredity, individual predisposition and genetic or familial susceptibility. Current studies are undermined by methodological and interpretative errors, especially regarding the diagnosis and measurements of root resorption from orthopantomographs and cephalograms. Samples are heterogeneous insofar as they comprise different clinical operators, varied types of planning, and in insufficient number, in view of the prevalence of tooth resorptions in the population. Nearly all biological events are coded and managed through genes, but this does not mean tooth resorptions are inherited, which can be demonstrated in heredograms and other methods of family studies. In orthodontic root resorption, one cannot possibly determine percentages of how much would be due to heredity or genetics, environmental factors and unknown factors. There is no need to lay the blame of tooth resorptions on events taking place outside the orthodontic realm since in the vast majority of cases, resorptions are not iatrogenic. In orthodontic practice, when all teeth are analyzed and planned using periapical radiography or computerized tomography, and when considering all predictive factors, tooth resorptions are not iatrogenic in nature and should be considered as one of the clinical events inherent in the treatment applied.

摘要

正畸移动引起的牙根吸收缺乏一致的科学证据支持,这些证据将其与遗传、个体易感性以及遗传或家族易感性联系起来。当前的研究受到方法学和解释性错误的影响,特别是在从全景片和头颅侧位片中诊断和测量牙根吸收方面。样本具有异质性,因为它们包括不同的临床操作者、不同类型的治疗计划,而且鉴于人群中牙齿吸收的普遍性,样本数量不足。几乎所有的生物事件都是通过基因编码和调控的,但这并不意味着牙齿吸收是可遗传的,这一点可以通过系谱图和其他家族研究方法得到证明。在正畸牙根吸收中,不可能确定有多少比例是由遗传或基因、环境因素以及未知因素导致的。没有必要将牙齿吸收归咎于正畸领域之外发生的事件,因为在绝大多数情况下,吸收并非医源性的。在正畸实践中,当使用根尖片或计算机断层扫描对所有牙齿进行分析和规划,并考虑所有预测因素时,牙齿吸收本质上并非医源性的,而应被视为所应用治疗中固有的临床事件之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6f/5573006/9e20367a858a/2176-9451-dpjo-22-04-00022-gf1.jpg

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