André Egidio Domingos, Pereira Renata Freire Alves, Snyder Robert Eugene, Machado Thamiris Santana, André Lialyz Soares Pereira, Cardoso Claudete Aparecida Araújo, Aguiar-Alves Fábio
Universidade Federal Fluminense, Laboratóro Universitário Rodolfo Albino, Laboratório de Epidemiologia e Biotecnologia Molecular, Niterói, RJ, Brasil.
Universidade Federal Fluminense, Instituto de Biologia, Programa de Pós-Graduação em Ciência e Biotecnologia, Niterói, RJ, Brasil.
Mem Inst Oswaldo Cruz. 2017 Sep;112(9):647-649. doi: 10.1590/0074-02760170040.
CC398 is a livestock-associated Staphylococcus aureus. However, it has also been isolated from humans with no previous contact with livestock. A surveillance of methicillin-resistant S. aureus colonisation among children attending public day care centres and hospitals in Niterói and Rio de Janeiro, Brazil, between 2011 and 2013, resulted in the isolation of six cases of CC398 from individuals with no previous exposure to livestock. These isolates showed a high frequency of the erm(C) gene (4/6, 66.7%) with induced resistance to clindamycin, and a relatively high frequency of SEs and lukS/lukF genes. These results suggest the emergence of a non-LA-CC398 in Brazil.
CC398是一种与家畜相关的金黄色葡萄球菌。然而，它也从之前未接触过家畜的人类中分离出来。2011年至2013年间，对巴西尼泰罗伊和里约热内卢的公立日托中心和医院儿童中的耐甲氧西林金黄色葡萄球菌定植情况进行监测，结果从之前未接触过家畜的个体中分离出6例CC398。这些分离株显示erm(C)基因的频率较高（4/6，66.7%），对克林霉素诱导耐药，并且SEs和lukS/lukF基因的频率相对较高。这些结果表明巴西出现了一种非家畜相关的CC398。
