Stoner Marie C D, Edwards Jessie K, Miller William C, Aiello Allison E, Halpern Carolyn T, Julien Aimée, Selin Amanda, Hughes James P, Wang Jing, Gomez-Olive Francesc Xavier, Wagner Ryan G, MacPhail Catherine, Kahn Kathleen, Pettifor Audrey
*Department of Epidemiology, University of North Carolina, Chapel Hill, NC; †Division of Epidemiology, The Ohio State University, Columbus, OH; ‡Department of Maternal and Child Health, University of North Carolina, Chapel Hill, NC; §Medical Research Council/Wits Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of the Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; ‖Department of Biostatistics, University of Washington, Seattle, WA; ¶Fred Hutchinson Cancer Research Center, Seattle, WA; #INDEPTH Network, Accra, Ghana; **Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Johannesburg, South Africa; ††School of Health and Society, University of Wollongong, NSW, Australia; and ‡‡Epidemiology and Global Health Unit, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
J Acquir Immune Defic Syndr. 2017 Dec 15;76(5):e107-e114. doi: 10.1097/QAI.0000000000001544.
Attending school may have a strong preventative association with sexually transmitted infections among young women, but the mechanism for this relationship is unknown. One hypothesis is that students who attend school practice safer sex with fewer partners, establishing safer sexual networks that make them less exposed to infection.
We used longitudinal data from a randomized controlled trial of young women aged 13-20 years in the Bushbuckridge district, South Africa, to determine whether the percentage of school days attended, school dropout, and grade repetition are associated with having a partner 5 or more years older (age-disparate) and with the number of sexual partners in the previous 12 months.
Risks of having an age-disparate relationship and number of sexual partners were compared using inverse probability of exposure weighted Poisson regression models. Generalized estimating equations were used to account for repeated measures.
Young women who attended fewer school days (<80%) and who dropped out of school were more likely to have an age-disparate relationship (risk difference 9.9%, 95% confidence interval [CI]: 3.9% to 16.0%; risk difference (%) dropout 17.2%, 95% CI: 5.4% to 29.0%) and those who dropped out reported having fewer partners (count difference dropout 0.343, 95% CI: 0.192 to 0.495). Grade repetition was not associated with either behavior.
Young women who less frequently attend school or who drop out are more likely to have an age-disparate relationship. Young women who drop out have overall more partners. These behaviors may increase the risk of exposure to HIV infection in young women out of school.
上学可能与年轻女性的性传播感染存在强有力的预防关联,但这种关系的机制尚不清楚。一种假设是,上学的学生与较少的性伴侣进行更安全性行为,建立起更安全的性网络,从而减少感染风险。
我们使用了来自南非布什巴克里奇地区一项针对13 - 20岁年轻女性的随机对照试验的纵向数据,以确定上学天数的百分比、辍学情况和留级是否与拥有年龄相差5岁或以上的伴侣(年龄差距较大)以及过去12个月中性伴侣的数量有关。
使用暴露加权泊松回归模型的逆概率来比较存在年龄差距关系和性伴侣数量的风险。采用广义估计方程来处理重复测量数据。
上学天数较少(<80%)和辍学的年轻女性更有可能拥有年龄差距较大的关系(风险差异9.9%,95%置信区间[CI]:3.9%至16.0%;辍学的风险差异(%)为17.2%,95% CI:5.4%至29.0%),且辍学的女性报告的性伴侣较少(计数差异辍学0.343,95% CI:0.192至0.495)。留级与这两种行为均无关联。
上学频率较低或辍学的年轻女性更有可能拥有年龄差距较大的关系。辍学的年轻女性总体上性伴侣更多。这些行为可能会增加校外年轻女性感染艾滋病毒的风险。