Abdelaziz Mohamed, Eziba Noura, Sharma Suash, Kleven Daniel, Al-Hendy Ayman
Department of Obstetrics & Gynecology, Augusta University, Augusta, GA, USA.
Department of Obstetrics and Gynecology, Mansoura Faculty of Medicine, Mansoura University Hospital, Mansoura, Egypt.
SAGE Open Med Case Rep. 2017 Sep 4;5:2050313X17726936. doi: 10.1177/2050313X17726936. eCollection 2017.
Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recognized neoplasm that mostly affects the vulvovaginal area. Our report discusses a case of cervical superficial myofibroblastoma of the lower female genital tract in a 45-year-old patient who is presented with menometrorrhagia. On examination, she had multiple uterine fibroids and a circumscribed submucosal mass lesion involving the anterior lip of cervix. At hysterectomy, histopathological examination of the cervical mass revealed a relatively hypocellular tumor consisted of bland spindled and stellate cells. An immunohistochemistry evaluation revealed reactivity for CD34, desmin, and smooth muscle actin. This neoplasm should be included in the differential diagnosis of cervical mass lesions. This tumor also needs to be differentiated from other mesenchymal lesions of lower female genital tract.
女性下生殖道浅表性肌成纤维细胞瘤是一种罕见的良性肿瘤,最近才被认识,主要累及外阴阴道区域。我们的报告讨论了一例45岁女性下生殖道宫颈浅表性肌成纤维细胞瘤病例,该患者表现为月经过多。检查时,她有多个子宫肌瘤以及一个累及宫颈前唇的局限性黏膜下肿块病变。子宫切除术中,宫颈肿块的组织病理学检查显示为一个细胞相对较少的肿瘤,由温和的梭形细胞和星状细胞组成。免疫组织化学评估显示对CD34、结蛋白和平滑肌肌动蛋白呈阳性反应。该肿瘤应列入宫颈肿块病变的鉴别诊断。此肿瘤还需要与女性下生殖道的其他间质性病变相鉴别。