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显微外科睾丸精子提取术

Microdissection testicular sperm extraction.

作者信息

Flannigan Ryan, Bach Phil V, Schlegel Peter N

机构信息

Weill Cornell Medicine, New York, NY, USA.

出版信息

Transl Androl Urol. 2017 Aug;6(4):745-752. doi: 10.21037/tau.2017.07.07.

DOI:10.21037/tau.2017.07.07
PMID:28904907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5583061/
Abstract

Microdissection testicular sperm extraction (microTESE) is considered the gold standard method for surgical sperm retrieval among patients with non-obstructive azoospermia (NOA). In this review, we will discuss the optimal evaluation of NOA patients and strategies to medically optimize NOA patients prior to microTESE. In addition, we will also discuss technical principles and pearls to maximize the chances of successful sperm retrieval, sperm retrieval rates (SRR) based upon testicular histology, predictors of successful sperm retrieval, gonadal recovery following microTESE, and potential complications.

摘要

显微切割睾丸取精术（microTESE）被认为是无梗阻性无精子症（NOA）患者手术取精的金标准方法。在本综述中，我们将讨论NOA患者的最佳评估方法以及在进行microTESE之前对NOA患者进行医学优化的策略。此外，我们还将讨论技术原则和技巧，以最大限度地提高成功取精的几率、基于睾丸组织学的取精率（SRR）、成功取精的预测因素、microTESE后的性腺恢复情况以及潜在并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef24/5583061/b275a552fed5/tau-06-04-745-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef24/5583061/af60fe277ee7/tau-06-04-745-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef24/5583061/b275a552fed5/tau-06-04-745-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef24/5583061/af60fe277ee7/tau-06-04-745-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef24/5583061/b275a552fed5/tau-06-04-745-f2.jpg

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J Assist Reprod Genet. 2017 Jan;34(1):149-154. doi: 10.1007/s10815-016-0812-3. Epub 2016 Sep 21.
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Impact of testicular histopathology as a predictor of sperm retrieval and pregnancy outcome in patients with nonobstructive azoospermia: correlation with clinical and hormonal factors.睾丸组织病理学对非梗阻性无精子症患者精子获取及妊娠结局预测的影响：与临床和激素因素的相关性
Andrologia. 2016 Sep;48(7):765-73. doi: 10.1111/and.12510. Epub 2015 Dec 20.
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人工智能在男性不育诊断和治疗中的当前及未来应用
Adv Exp Med Biol. 2025;1469:1-23. doi: 10.1007/978-3-031-82990-1_1.
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Fresh versus frozen micro-TESE sperm and outcomes.新鲜与冷冻的显微睾丸精子提取术精子及结果
Asian J Androl. 2025 May 1;27(3):399-408. doi: 10.4103/aja202513. Epub 2025 Apr 18.
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