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Modular Approach to pseudo-Neoclerodanes as Designer κ-Opioid Ligands.
Org Lett. 2017 Oct 6;19(19):5414-5417. doi: 10.1021/acs.orglett.7b02684. Epub 2017 Sep 14.
2
Synthesis of salvinorin A analogues as opioid receptor probes.
J Nat Prod. 2006 Jun;69(6):914-8. doi: 10.1021/np060094b.
3
Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.
J Med Chem. 2005 Jul 28;48(15):4765-71. doi: 10.1021/jm048963m.
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Salvinorin A: a novel and highly selective kappa-opioid receptor agonist.
Life Sci. 2004 Oct 15;75(22):2615-9. doi: 10.1016/j.lfs.2004.07.008.
6
Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.
Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11934-9. doi: 10.1073/pnas.182234399. Epub 2002 Aug 21.
7
Semisynthetic neoclerodanes as kappa opioid receptor probes.
Bioorg Med Chem. 2012 May 1;20(9):3100-10. doi: 10.1016/j.bmc.2012.02.040. Epub 2012 Mar 1.
8
Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues.
J Med Chem. 2014 Dec 26;57(24):10464-75. doi: 10.1021/jm501521d. Epub 2014 Dec 9.
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Semisynthesis and Kappa-Opioid Receptor Activity of Derivatives of Columbin, a Furanolactone Diterpene.
J Nat Prod. 2017 Jul 28;80(7):2094-2100. doi: 10.1021/acs.jnatprod.7b00327. Epub 2017 Jul 18.
10
Salvinorin A: the "magic mint" hallucinogen finds a molecular target in the kappa opioid receptor.
Trends Pharmacol Sci. 2003 Mar;24(3):107-9. doi: 10.1016/S0165-6147(03)00027-0.

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A Route to Potent, Selective, and Biased Salvinorin Chemical Space.
ACS Cent Sci. 2023 Jul 12;9(8):1567-1574. doi: 10.1021/acscentsci.3c00616. eCollection 2023 Aug 23.
2
Formal Total Synthesis of Salvinorin A.
ChemistryOpen. 2022 Oct;11(10):e202200015. doi: 10.1002/open.202200015. Epub 2022 Feb 26.
3
A Protecting-Group-Free Synthesis of (-)-Salvinorin A.
Chemistry. 2021 May 20;27(29):7968-7973. doi: 10.1002/chem.202100560. Epub 2021 May 2.
4
Natural Products for the Treatment of Pain: Chemistry and Pharmacology of Salvinorin A, Mitragynine, and Collybolide.
Biochemistry. 2021 May 11;60(18):1381-1400. doi: 10.1021/acs.biochem.0c00629. Epub 2020 Sep 22.
5
Chemical syntheses of the salvinorin chemotype of KOR agonist.
Nat Prod Rep. 2020 Nov 18;37(11):1478-1496. doi: 10.1039/d0np00028k.
6
Cutting-Edge Search for Safer Opioid Pain Relief: Retrospective Review of Salvinorin A and Its Analogs.
Front Psychiatry. 2019 Mar 27;10:157. doi: 10.3389/fpsyt.2019.00157. eCollection 2019.
7
A review of salvinorin analogs and their kappa-opioid receptor activity.
Bioorg Med Chem Lett. 2018 May 15;28(9):1436-1445. doi: 10.1016/j.bmcl.2018.03.029. Epub 2018 Mar 12.
8
Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist.
ACS Cent Sci. 2017 Dec 27;3(12):1329-1336. doi: 10.1021/acscentsci.7b00488. Epub 2017 Dec 13.

本文引用的文献

4
Total Synthesis of (-)-Salvinorin A.
Chemistry. 2016 Dec 12;22(50):17983-17986. doi: 10.1002/chem.201604853. Epub 2016 Nov 4.
5
Time course of pharmacokinetic and hormonal effects of inhaled high-dose salvinorin A in humans.
J Psychopharmacol. 2016 Apr;30(4):323-9. doi: 10.1177/0269881116629125. Epub 2016 Feb 15.
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Opioid Receptors.
Annu Rev Med. 2016;67:433-51. doi: 10.1146/annurev-med-062613-093100. Epub 2015 Aug 26.
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Organocatalytic enantioselective α-hydroxymethylation of aldehydes: mechanistic aspects and optimization.
J Org Chem. 2015 Apr 17;80(8):4030-45. doi: 10.1021/acs.joc.5b00380. Epub 2015 Apr 3.
8
Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues.
J Med Chem. 2014 Dec 26;57(24):10464-75. doi: 10.1021/jm501521d. Epub 2014 Dec 9.
9
Palladium-catalyzed transformations of salvinorin A, a neoclerodane diterpene from Salvia divinorum.
Org Lett. 2013 Dec 6;15(23):5936-9. doi: 10.1021/ol4027528. Epub 2013 Nov 18.
10
The 2-methoxy methyl analogue of salvinorin A attenuates cocaine-induced drug seeking and sucrose reinforcements in rats.
Eur J Pharmacol. 2013 Nov 15;720(1-3):69-76. doi: 10.1016/j.ejphar.2013.10.050. Epub 2013 Nov 4.

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