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血糖传感器的最新进展。

Recent developments in blood glucose sensors.

作者信息

Wang Hui-Chen, Lee An-Rong

机构信息

Institute of Pharmaceutics, Development Center for Biotechnology, New Taipei City, Taiwan.

School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.

出版信息

J Food Drug Anal. 2015 Jun;23(2):191-200. doi: 10.1016/j.jfda.2014.12.001. Epub 2015 Feb 14.

Abstract

Diabetes has recently become a leading cause of death worldwide. To date, although there is no means to cure or prevent diabetes, appropriate medication and blood sugar monitoring can enhance treatment efficiency, alleviate the symptoms, and diminish the complications of the condition. This review article deals with current growth areas in the market for blood glucose sensors and possible future alternatives, which are generally considered to be the point sample test and the continuous glucose monitor (CGM). Most glucose sensors are enzyme-based, whereas others are enzyme-free. The former class is sensitive and some products are extensively employed for daily self-sensing and in hospital environments as reliable diagnostic tools. The latter class, particularly the boronic acid fluorescent sensor, is facile and extremely promising. Practicality demands that all types of sensors offer accuracy, specificity, and real-time detection.

摘要

糖尿病最近已成为全球主要死因。迄今为止,尽管尚无治愈或预防糖尿病的方法,但适当的药物治疗和血糖监测可以提高治疗效率、缓解症状并减少该疾病的并发症。这篇综述文章探讨了血糖传感器市场当前的增长领域以及未来可能的替代方案,通常认为是点样检测和连续血糖监测(CGM)。大多数葡萄糖传感器基于酶,而其他的则无酶。前一类传感器灵敏度高,一些产品广泛用于日常自我检测以及医院环境中作为可靠的诊断工具。后一类,特别是硼酸荧光传感器,使用简便且极具前景。实际应用要求所有类型的传感器都具备准确性、特异性和实时检测能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6adf/9351764/6aaba4996fb4/jfda-23-02-191f1.jpg

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