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经股动脉经导管主动脉瓣置换术采用监护麻醉与全身麻醉的患者选择及结果

Patient Selection and Outcomes of Transfemoral Transcatheter Aortic Valve Replacement Performed with Monitored Anesthesia Care Versus General Anesthesia.

作者信息

Pani Saroj, Cagino John, Feustel Paul, Musuku Sridhar Reddy, Raja Asim, Bruno Natalie, Ursillo Christopher, Arunakul Nathapong, Poulos Constantine M, Welljams-Dorof Michael, Roberts Kevin, Torosoff Mikhail, Delago Augustine

机构信息

Department of Anesthesiology, Albany Medical Center Hospital, Albany, NY.

Department of Anesthesiology, Albany Medical Center Hospital, Albany, NY.

出版信息

J Cardiothorac Vasc Anesth. 2017 Dec;31(6):2049-2054. doi: 10.1053/j.jvca.2017.04.005. Epub 2017 Apr 5.

DOI:10.1053/j.jvca.2017.04.005
PMID:28911896
Abstract

OBJECTIVE

The aim of this study was to compare outcomes of monitored anesthesia care (MAC) versus general anesthesia (GA) for transfemoral transcatheter aortic valve replacement (TF-TAVR) and to describe a selection process for the administration of MAC.

DESIGN

Retrospective analysis of patients who underwent TF-TAVR under MAC or GA.

SETTING

Department of Cardiac Anesthesia, Albany Medical Center, a tertiary university hospital.

PARTICIPANTS

Patients selected for TF-TAVR.

INTERVENTIONS

Patients were divided into those who underwent MAC and those who underwent GA.

MEASUREMENTS AND MAIN RESULTS

The study comprised 104 consecutive patients (55% male, mean age 83 years) who underwent TF-TAVR under MAC (n = 60) or GA (n = 37) from 2014 to 2015. Seven patients were converted from MAC to GA and were omitted from analysis. There was no statistically significant difference between 30-day mortality and complications between the 2 groups. The MAC group had a significantly shorter median intensive care unit length of stay (48 h v 74 h, p = 0.0002). The MAC group also demonstrated reduced procedural time (45.5 min v 62 min, p = 0.003); operating room time (111 min v 153 min, p = <0.001); and fluoroscopy time (650 s v 690 s, p = 0.03).

CONCLUSIONS

Patient selection for TF-TAVR with MAC can be formalized and implemented successfully. MAC allows for the minimizing of patient exposure to unnecessary interventions and improving resource utilization in suitable TAVR patients. Selection requires a multidisciplinary clinical decision-making process. MAC demonstrates good outcomes compared with GA, yet it is important to have a cardiac anesthesiologist present in the event of emergency conversion to GA.

摘要

目的

本研究旨在比较监测麻醉管理(MAC)与全身麻醉(GA)用于经股动脉经导管主动脉瓣置换术(TF-TAVR)的效果,并描述MAC给药的选择过程。

设计

对接受MAC或GA下TF-TAVR的患者进行回顾性分析。

地点

三级大学医院奥尔巴尼医疗中心心脏麻醉科。

参与者

入选TF-TAVR的患者。

干预措施

患者分为接受MAC的患者和接受GA的患者。

测量指标及主要结果

本研究纳入了2014年至2015年期间连续接受MAC(n = 60)或GA(n = 37)下TF-TAVR的104例患者(55%为男性,平均年龄83岁)。7例患者从MAC转为GA,被排除在分析之外。两组之间30天死亡率和并发症无统计学显著差异。MAC组的重症监护病房中位住院时间显著更短(48小时对74小时,p = 0.0002)。MAC组的手术时间也缩短(45.5分钟对62分钟,p = 0.003);手术室时间(111分钟对153分钟,p = <0.001);以及透视时间(650秒对690秒,p = 0.03)。

结论

TF-TAVR选择MAC进行患者管理可以成功地规范化和实施。MAC能够使合适的TAVR患者尽量减少不必要的干预,并提高资源利用效率。选择需要多学科临床决策过程。与GA相比,MAC显示出良好的效果,但在紧急转为GA的情况下,有心脏麻醉医生在场很重要。

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