Suzuki Shunji
Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, 5-11-12 Tateishi, Katsushika-ku, Tokyo 124-0012, Japan. Email:
J Clin Med Res. 2017 Oct;9(10):860-863. doi: 10.14740/jocmr3148w. Epub 2017 Sep 1.
The aim of this study was to compare the obstetric outcomes of twin pregnancies between Japanese women aged ≥ 40 years and their younger counterparts aged 25 - 29.
This was a retrospective study of twin pregnancies managed at Japanese Red Cross Katsushika Maternity Hospital between 2002 and 2016. Women aged 40 and older at delivery (n = 117) were compared with women aged 25 - 29 at delivery (n = 536).
Although the women ≥ 40 years old were more likely to have increased risks of HELLP (hemolytic, elevated liver enzymes and low platelet) syndrome and very low birth weight neonates, there were no measurable differences in obstetric outcomes such as hypertensive disorders, premature delivery and neonatal asphyxia between the two groups.
Advanced maternal age did not seem to affect obstetric outcomes in twin pregnancies seriously.
本研究的目的是比较年龄≥40岁的日本女性与年龄在25 - 29岁的年轻女性双胎妊娠的产科结局。
这是一项对2002年至2016年在日本红十字胜哄妇产医院管理的双胎妊娠进行的回顾性研究。将分娩时年龄≥40岁的女性（n = 117）与分娩时年龄在25 - 29岁的女性（n = 536）进行比较。
尽管≥40岁的女性发生HELLP（溶血、肝酶升高和血小板减少）综合征及极低出生体重新生儿的风险更高，但两组在高血压疾病、早产和新生儿窒息等产科结局方面没有可测量的差异。
高龄似乎并未严重影响双胎妊娠的产科结局。
