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子宫内膜癌的腹腔镜分期:它对生存率有影响吗?

Laparoscopic staging of endometrial cancer: Does it have any impact on survival?

作者信息

Şenol Taylan, Polat Mesut, Şanverdi İlhan, Özkaya Enis, Karateke Ateş

机构信息

Zeynep Kamil Training and Research Hospital, Clinic of Women and Children's Health, İstanbul, Turkey.

出版信息

Turk J Obstet Gynecol. 2015 Sep;12(3):139-143. doi: 10.4274/tjod.78466. Epub 2015 Sep 15.

Abstract

OBJECTIVE

To assess whether laporoscopic approach to endometrial cancer is associated with survival.

MATERIALS AND METHODS

In total, 158 patients with endometrial cancer underwent staging surgery at a tertiary referral center, 30 of whom underwent laparoscopy, whereas the remainder received treatment with a conventional approach. Survival between groups was analyzed.

RESULTS

The comparison of the groups revealed similar disease-free survival (p=0.791). Histology, cervical, adnexal and serosal involvement were found to be significantly correlated with recurrence in the laparoscopically staged group, whereas CA 125, histology, tumor grade, tumor diameter, cervical involvement, degree of myometrial invasion, adnexal and serosal involvement, and pelvic metastasis were significanly correlated with recurrence in the conventionally managed group.

CONCLUSION

Laparoscopic approach to endometrial cancer, along with its widely accepted postoperative advantages, has similar disease-free survival but different variables affect recurrence rates.

摘要

目的

评估子宫内膜癌的腹腔镜手术方法是否与生存率相关。

材料与方法

共有158例子宫内膜癌患者在一家三级转诊中心接受分期手术,其中30例接受了腹腔镜检查,其余患者采用传统方法治疗。分析了两组之间的生存率。

结果

两组比较显示无病生存率相似(p = 0.791)。在腹腔镜分期组中,发现组织学、宫颈、附件和浆膜受累与复发显著相关,而在传统治疗组中,CA 125、组织学、肿瘤分级、肿瘤直径、宫颈受累、肌层浸润程度、附件和浆膜受累以及盆腔转移与复发显著相关。

结论

子宫内膜癌的腹腔镜手术方法,除了其术后被广泛认可的优势外,具有相似的无病生存率,但不同的变量会影响复发率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3556/5558387/b1c213078708/TJOD-12-139-g4.jpg

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