宫内人工授精周期中的黄体期支持
Luteal phase support in intrauterine insemination cycles.
作者信息
Gün İsmet, Özdamar Özkan, Yılmaz Ali
机构信息
Gülhane Military Medical Academy, Haydarpaşa Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey.
İstanbul Medeniyet University Faculty of Medicine, Department of Obstetrics and Gynecology, İstanbul, Turkey.
出版信息
Turk J Obstet Gynecol. 2016 Jun;13(2):90-94. doi: 10.4274/tjod.89577. Epub 2016 Jun 15.
Abstract
Intrauterine insemination (IUI) treatment aims to increase the rate of conception by increasing the chances that the maximum number of healthy sperm reach the site of fertilization. IUI with controlled ovarian stimulation is frequently used in assisted reproduction practice. Although widely used, the efficacy of luteal support in IUI remains controversial. In this article, we aimed to review what we know regarding luteal support in IUI cycles and to adjudicate about the clinical use and benefits of this treatment. Based on the study results available in the literature, it appears to be beneficial to supplement the luteal phase in gonadotropin-stimulated IUI cycles that yield more than one follicle.
摘要
宫腔内人工授精（IUI）治疗旨在通过增加尽可能多的健康精子到达受精部位的机会来提高受孕率。控制性卵巢刺激下的宫腔内人工授精在辅助生殖实践中经常使用。尽管广泛应用，但宫腔内人工授精中黄体支持的疗效仍存在争议。在本文中，我们旨在回顾我们对宫腔内人工授精周期中黄体支持的了解，并对这种治疗的临床应用和益处做出评判。根据文献中的研究结果，在促性腺激素刺激下产生多个卵泡的宫腔内人工授精周期中补充黄体期似乎是有益的。
相似文献
1
Luteal phase support in intrauterine insemination cycles.宫内人工授精周期中的黄体期支持
Turk J Obstet Gynecol. 2016 Jun;13(2):90-94. doi: 10.4274/tjod.89577. Epub 2016 Jun 15.
2
Timed intercourse versus intra-uterine insemination with or without ovarian hyperstimulation for subfertility in men.男性不育症采用定时性交与宫内人工授精（无论是否进行卵巢超刺激）的比较
Cochrane Database Syst Rev. 2000(2):CD000360. doi: 10.1002/14651858.CD000360.
3
Should luteal phase support be introduced in ovarian stimulation/IUI programmes? An evidence-based review.黄体支持是否应引入卵巢刺激/人工授精方案？基于证据的综述。
Reprod Biomed Online. 2009;19 Suppl 4:4239.
4
Luteal Phase Support in the Intrauterine Insemination (IUI) Cycles: A Randomized Double Blind, Placebo Controlled Study.宫腔内人工授精（IUI）周期中的黄体期支持：一项随机双盲、安慰剂对照研究。
J Family Reprod Health. 2014 Dec;8(4):149-53.
5
Does Luteal Phase Support Effect Pregnancy Rates in Intrauterine Insemination Cycles? A Prospective Randomised Controlled Study in a Tertiary Center.黄体期支持对宫腔内人工授精周期妊娠率有影响吗？一项在三级中心进行的前瞻性随机对照研究。
Obstet Gynecol Int. 2020 Aug 5;2020:6234070. doi: 10.1155/2020/6234070. eCollection 2020.
6
Impact of luteal phase support on pregnancy rates in intrauterine insemination cycles: a prospective randomized study.黄体期支持对宫腔内人工授精周期妊娠率的影响：一项前瞻性随机研究。
Fertil Steril. 2009 Jun;91(6):2508-13. doi: 10.1016/j.fertnstert.2008.04.029. Epub 2008 Aug 9.
7
8
Success of intrauterine insemination using cryopreserved donor sperm is related to the age of the woman and the number of preovulatory follicles.使用冷冻供体精子进行宫腔内人工授精的成功率与女性年龄及排卵前卵泡数量有关。
J Assist Reprod Genet. 1996 Apr;13(4):310-4. doi: 10.1007/BF02070144.
9
The effect of luteal-phase support with vaginal progesterone on pregnancy rates in gonadotropin and clomiphene citrate/intra-uterine insemination cycles in unexplained infertility: A prospective randomised study.黄体期阴道用黄体酮支持对不明原因不孕症患者在促性腺激素和枸橼酸氯米芬/宫腔内人工授精周期中妊娠率的影响：一项前瞻性随机研究。
J Obstet Gynaecol. 2016 Aug;36(6):794-799. doi: 10.3109/01443615.2016.1154511. Epub 2016 May 5.
10
Predictive value of mid luteal progesterone concentration before luteal support in controlled ovarian hyperstimulation with intrauterine insemination.在控制性卵巢过度刺激并宫腔内人工授精中，黄体支持前黄体中期孕酮浓度的预测价值。
Aust N Z J Obstet Gynaecol. 2004 Feb;44(1):51-6. doi: 10.1111/j.1479-828X.2004.00160.x.
引用本文的文献
1
Luteal Phase Support in Intrauterine Insemination Cycles: A Randomized Clinical Trial of Vaginal Versus Intramuscular Progesterone Administration.宫腔内人工授精周期中的黄体期支持：阴道给药与肌肉注射黄体酮的随机临床试验
J Reprod Infertil. 2022 Jan-Mar;23(1):33-38. doi: 10.18502/jri.v23i1.8450.
2
Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse.宫腔内人工授精或性交尝试妊娠妇女的黄体支持。
Cochrane Database Syst Rev. 2022 Aug 24;8(8):CD012396. doi: 10.1002/14651858.CD012396.pub2.
3
Does Luteal Phase Support Effect Pregnancy Rates in Intrauterine Insemination Cycles? A Prospective Randomised Controlled Study in a Tertiary Center.黄体期支持对宫腔内人工授精周期妊娠率有影响吗？一项在三级中心进行的前瞻性随机对照研究。
Obstet Gynecol Int. 2020 Aug 5;2020:6234070. doi: 10.1155/2020/6234070. eCollection 2020.
本文引用的文献
1
Comparison of oral dydrogesterone with vaginal progesteronefor luteal support in IUI cycles: a randomized clinical trial.口服地屈孕酮与阴道用黄体酮在人工授精周期黄体支持中的比较：一项随机临床试验。
Iran J Reprod Med. 2015 Jul;13(7):433-8.
2
Luteal Phase Support in the Intrauterine Insemination (IUI) Cycles: A Randomized Double Blind, Placebo Controlled Study.宫腔内人工授精（IUI）周期中的黄体期支持：一项随机双盲、安慰剂对照研究。
J Family Reprod Health. 2014 Dec;8(4):149-53.
3
4
Efficacy of luteal phase support with vaginal progesterone in intrauterine insemination: a systematic review and meta-analysis.黄体期支持治疗在宫腔内人工授精中的疗效：系统评价和荟萃分析。
J Assist Reprod Genet. 2014 Jan;31(1):89-100. doi: 10.1007/s10815-013-0127-6. Epub 2013 Nov 6.
5
Progesterone luteal support after ovulation induction and intrauterine insemination: a systematic review and meta-analysis.排卵诱导和宫腔内人工授精后黄体支持的孕激素：系统评价和荟萃分析。
Fertil Steril. 2013 Nov;100(5):1373-80. doi: 10.1016/j.fertnstert.2013.06.034. Epub 2013 Jul 19.
6
Assisted reproductive technology in Europe, 2009: results generated from European registers by ESHRE.欧洲 2009 年辅助生殖技术：ESHRE 欧洲注册中心获得的结果。
Hum Reprod. 2013 Sep;28(9):2318-31. doi: 10.1093/humrep/det278. Epub 2013 Jul 9.
7
The effect of progesterone supplementation on pregnancy rates in controlled ovarian stimulation and intrauterine insemination cycles: a randomized prospective trial.孕激素补充对控制性卵巢刺激和宫腔内人工授精周期妊娠率的影响：一项随机前瞻性试验。
Eur J Obstet Gynecol Reprod Biol. 2012 Dec;165(2):249-53. doi: 10.1016/j.ejogrb.2012.08.007. Epub 2012 Aug 30.
8
Luteal phase support for assisted reproduction cycles.辅助生殖周期的黄体期支持。
Cochrane Database Syst Rev. 2011 Oct 5(10):CD009154. doi: 10.1002/14651858.CD009154.pub2.
9
Luteal phase support may improve pregnancy outcomes during intrauterine insemination cycles.黄体期支持可能会改善宫腔内人工授精周期中的妊娠结局。
Eur J Obstet Gynecol Reprod Biol. 2011 Jul;157(1):57-62. doi: 10.1016/j.ejogrb.2011.03.022. Epub 2011 Apr 21.
10
Luteal phase support in normo-ovulatory women stimulated with clomiphene citrate for intrauterine insemination: need or habit?克罗米酚刺激排卵的正常排卵妇女黄体支持：需要还是习惯？
Hum Reprod. 2010 Oct;25(10):2501-6. doi: 10.1093/humrep/deq223. Epub 2010 Aug 18.
Zotero 插件