Zöllner Johann Philipp, Haag Anja, Hermsen Anke, Bauer Sebastian, Stahl Friederike, Wulf Karina, Menzler Katja, Reif Philipp S, Wagner Marlies, Pagenstecher Axel, Sure Ulrich, Knake Susanne, Rosenow Felix, Strzelczyk Adam
Department of Neurology and Epilepsy Center Frankfurt Rhine-Main, Goethe-University, Frankfurt am Main, Germany.
Department of Neurology and Epilepsy Center Hessen, Philipps-University, Marburg, Germany.
Epilepsy Behav Case Rep. 2017 Aug 3;8:55-62. doi: 10.1016/j.ebcr.2017.07.003. eCollection 2017.
The aim of these two case reports is to demonstrate that a predefined, structured, multimodal clinical bed-side testing during seizures in a long-term video-EEG monitoring setting facilitates diagnosis of complex neuropsychological syndromes. To the best of our knowledge, we present the first case of conduction aphasia as the sole ictal semiology, and a patient with focal seizures producing an angular gyrus syndrome in the speech dominant hemisphere. The relevance of diagnosing ictal aphasic and angular gyrus syndromes and localizing the symptomatogenic zone is discussed. Current pathophysiological concepts are presented regarding conduction aphasia and Gerstmann's syndrome.
这两篇病例报告的目的是证明，在长期视频脑电图监测环境下，在癫痫发作期间进行预先定义的、结构化的、多模式临床床边测试有助于诊断复杂的神经心理学综合征。据我们所知，我们呈现了首例以传导性失语作为唯一发作期症状学表现的病例，以及一名在语言优势半球发生局灶性癫痫发作并产生角回综合征的患者。文中讨论了诊断发作期失语和角回综合征以及定位症状发生区域的相关性。本文还介绍了关于传导性失语和格斯特曼综合征的当前病理生理学概念。
