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男同性恋和双性恋者在有口服暴露前预防（PrEP）的情况下，是否会在长效注射型 PrEP 问世后转而使用长效注射型 PrEP？

Will Gay and Bisexual Men Taking Oral Pre-exposure Prophylaxis (PrEP) Switch to Long-Acting Injectable PrEP Should It Become Available?

机构信息

Center for HIV/AIDS Educational Studies & Training, Hunter College of the City University of New York (CUNY), New York, NY, USA.

Health Psychology and Clinical Science Doctoral Program, The Graduate Center of the City University of New York (CUNY), New York, NY, USA.

出版信息

AIDS Behav. 2018 Apr;22(4):1184-1189. doi: 10.1007/s10461-017-1907-2.

DOI:10.1007/s10461-017-1907-2
PMID:28913659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5851796/
Abstract

Oral pre-exposure prophylaxis (PrEP) is highly effective at reducing HIV transmission risk and is CDC recommended for many gay, bisexual, and other men who have sex with men (GBM). We sought to investigate awareness of and preference for using long-acting injectable PrEP (LAI-PrEP) among GBM currently taking oral PrEP (n = 104), and identify their concerns. About half of GBM had heard of LAI-PrEP, and 30.8% specifically preferred LAI-PrEP. GBM with more concerns about the level of protection and drug half-life of LAI-PrEP had lower odds of preferring LAI-PrEP. Given that daily pill adherence is a challenge for some on PrEP, it is important to investigate the degree to which those on PrEP might consider LAI-PrEP as an alternative.

摘要

口服暴露前预防 (PrEP) 可有效降低 HIV 传播风险，疾病预防控制中心 (CDC) 建议许多男同性恋者、双性恋者和其他与男性发生性关系者 (GBM) 使用。我们试图调查目前正在服用口服 PrEP (n=104) 的 GBM 对长效注射型 PrEP (LAI-PrEP) 的知晓率和偏好，并确定他们的关注点。大约一半的 GBM 听说过 LAI-PrEP，30.8% 的人特别喜欢 LAI-PrEP。对 LAI-PrEP 的保护水平和药物半衰期更关注的 GBM 选择 LAI-PrEP 的可能性较低。鉴于每日服药依从性对一些 PrEP 使用者来说是一个挑战，因此有必要研究 PrEP 使用者中有多少人可能会考虑将 LAI-PrEP 作为替代方案。

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