1 University of California, San Diego, USA.
2 Rady Children's Hospital, San Diego, USA.
Autism. 2018 Nov;22(8):938-952. doi: 10.1177/1362361317712650. Epub 2017 Sep 15.
Publicly funded mental health programs play a significant role in serving children with autism spectrum disorder. Understanding patterns of psychiatric comorbidity for this population within mental health settings is important to implement appropriately tailored interventions. This study (1) describes patterns of psychiatric comorbidity in children with autism spectrum disorder who present to mental health services with challenging behaviors and (2) identifies child characteristics associated with comorbid conditions. Data are drawn from baseline assessments from 201 children with autism spectrum disorder who participated in a community effectiveness trial across 29 publicly funded mental health programs. Non-autism spectrum disorder diagnoses were assessed using an adapted Mini-International Neuropsychiatric Interview, parent version. Approximately 92% of children met criteria for at least one non-autism spectrum disorder diagnosis (78% attention deficit hyperactivity disorder, 58% oppositional defiant disorder, 56% anxiety, 30% mood). Logistic regression indicated that child gender and clinical characteristics were differentially associated with meeting criteria for attention deficit hyperactivity disorder, oppositional defiant disorder, an anxiety, or a mood disorder. Exploratory analyses supported a link between challenging behaviors and mood disorder symptoms and revealed high prevalence of these symptoms in this autism spectrum disorder population. Findings provide direction for tailoring intervention to address a broad range of clinical issues for youth with autism spectrum disorder served in mental health settings.
公共资助的心理健康计划在为自闭症谱系障碍儿童提供服务方面发挥着重要作用。了解精神卫生机构中这一人群的精神共病模式对于实施适当的针对性干预措施非常重要。本研究(1)描述了在精神卫生服务机构中出现行为问题的自闭症谱系障碍儿童的精神共病模式,(2)确定了与共病相关的儿童特征。数据来自参加了 29 个公共资助的心理健康项目的 201 名自闭症谱系障碍儿童的基线评估。使用改良的 Mini-International Neuropsychiatric Interview(儿童版)评估非自闭症谱系障碍诊断。大约 92%的儿童符合至少一种非自闭症谱系障碍诊断标准(78%注意力缺陷多动障碍、58%对立违抗性障碍、56%焦虑症、30%心境障碍)。逻辑回归表明,儿童性别和临床特征与注意力缺陷多动障碍、对立违抗性障碍、焦虑症或心境障碍的诊断标准存在差异。探索性分析支持行为问题与心境障碍症状之间存在联系,并揭示了自闭症谱系障碍人群中这些症状的高患病率。研究结果为针对在精神卫生机构中服务的自闭症谱系障碍青年的广泛临床问题调整干预措施提供了方向。