Jones Christopher, Twoon Mark, Ho Weiguang, Portelli Mark, Robertson Bernard F, Anderson William
Plastic and Reconstructive Surgery Department, St John's Hospital, Livingston, UK.
Department of Plastic Surgery, Ulster Hospital, Belfast, UK.
J Cutan Pathol. 2018 Jan;45(1):33-38. doi: 10.1111/cup.13046. Epub 2017 Oct 18.
Pilomatrix carcinoma is a rare, locally aggressive tumor with a tendency to recur. Distant metastases have been reported, with pulmonary lesions being the most frequent manifestation. Similar to pilomatrixoma, pilomatrix carcinoma typically presents as a nontender, firm dermal swelling and is found most commonly in the head and neck region. Although pilomatrixomas and pilomatrix carcinoma are well-recognized lesions, clinically they are frequently misdiagnosed as other skin conditions. By reviewing the literature over the past 10 years, the aims of this review are to analyze the cause, clinical presentation, histopathologic features, management and outcomes of pilomatrix carcinoma amongst children and adults.
毛母质癌是一种罕见的、具有局部侵袭性且有复发倾向的肿瘤。已有远处转移的报道,肺部病变是最常见的表现形式。与毛母质瘤相似,毛母质癌通常表现为无压痛的坚实性真皮肿胀,最常见于头颈部区域。尽管毛母质瘤和毛母质癌是已被充分认识的病变,但临床上它们常被误诊为其他皮肤疾病。通过回顾过去10年的文献,本综述的目的是分析儿童和成人毛母质癌的病因、临床表现、组织病理学特征、治疗及预后。