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毛母质癌:12年经验及文献综述

Pilomatrix carcinoma: 12-year experience and review of the literature.

作者信息

Jones Christopher, Twoon Mark, Ho Weiguang, Portelli Mark, Robertson Bernard F, Anderson William

机构信息

Plastic and Reconstructive Surgery Department, St John's Hospital, Livingston, UK.

Department of Plastic Surgery, Ulster Hospital, Belfast, UK.

出版信息

J Cutan Pathol. 2018 Jan;45(1):33-38. doi: 10.1111/cup.13046. Epub 2017 Oct 18.

DOI:10.1111/cup.13046
PMID:28914451
Abstract

Pilomatrix carcinoma is a rare, locally aggressive tumor with a tendency to recur. Distant metastases have been reported, with pulmonary lesions being the most frequent manifestation. Similar to pilomatrixoma, pilomatrix carcinoma typically presents as a nontender, firm dermal swelling and is found most commonly in the head and neck region. Although pilomatrixomas and pilomatrix carcinoma are well-recognized lesions, clinically they are frequently misdiagnosed as other skin conditions. By reviewing the literature over the past 10 years, the aims of this review are to analyze the cause, clinical presentation, histopathologic features, management and outcomes of pilomatrix carcinoma amongst children and adults.

摘要

毛母质癌是一种罕见的、具有局部侵袭性且有复发倾向的肿瘤。已有远处转移的报道,肺部病变是最常见的表现形式。与毛母质瘤相似,毛母质癌通常表现为无压痛的坚实性真皮肿胀,最常见于头颈部区域。尽管毛母质瘤和毛母质癌是已被充分认识的病变,但临床上它们常被误诊为其他皮肤疾病。通过回顾过去10年的文献,本综述的目的是分析儿童和成人毛母质癌的病因、临床表现、组织病理学特征、治疗及预后。

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1
Pilomatrix carcinoma: 12-year experience and review of the literature.毛母质癌:12年经验及文献综述
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引用本文的文献

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Malignant adnexal skin tumors: A 15-year case series analysis from a Latin-American institution.恶性附属器皮肤肿瘤:来自拉丁美洲一家机构的15年病例系列分析。
Int J Surg Case Rep. 2025 Aug 26;135:111852. doi: 10.1016/j.ijscr.2025.111852.
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A case of pilomatrix carcinoma found in the shoulder.一例发生于肩部的毛母质癌。
J Surg Case Rep. 2025 Aug 4;2025(8):rjaf574. doi: 10.1093/jscr/rjaf574. eCollection 2025 Aug.
3
Uterine endometrioid adenocarcinoma with pilomatrix-like differentiation: A case report and review of the literature.
具有毛母质瘤样分化的子宫内膜样腺癌:一例报告并文献复习
Gynecol Oncol Rep. 2025 Feb 9;57:101693. doi: 10.1016/j.gore.2025.101693. eCollection 2025 Feb.
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Case report: Periorbital pilomatricoma: a rare benign skin tumor misdiagnosed as cellulitis.病例报告:眶周毛母质瘤:一种被误诊为蜂窝织炎的罕见良性皮肤肿瘤。
Front Ophthalmol (Lausanne). 2025 Jan 23;5:1503693. doi: 10.3389/fopht.2025.1503693. eCollection 2025.
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Pilomatrix carcinoma unveiled: a systematic review of clinical characteristics, pathogenesis, diagnostic puzzles, and management strategies.毛母质癌揭秘:临床特征、发病机制、诊断难题及管理策略的系统评价
Arch Dermatol Res. 2025 Jan 18;317(1):278. doi: 10.1007/s00403-024-03543-7.
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Pilomatrix Carcinoma: A Benign-Mimic with Malignant Consequences - A Case Report and Review of the Current Literature.毛母质癌:一种具有恶性后果的良性模仿者——病例报告及当前文献综述
Case Rep Dermatol. 2024 Jun 18;16(1):156-163. doi: 10.1159/000539123. eCollection 2024 Jan-Dec.
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Metastatic pilomatrix carcinoma treated with stereotactic body radiation therapy.立体定向体部放射治疗转移性毛母质癌。
JAAD Case Rep. 2024 Mar 15;47:50-53. doi: 10.1016/j.jdcr.2024.02.032. eCollection 2024 May.
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Giant pilomatrix carcinoma of the scalp with intracranial extension: A case report.头皮巨大毛母质癌伴颅内侵犯:一例报告。
Clin Case Rep. 2023 Nov 4;11(11):e8123. doi: 10.1002/ccr3.8123. eCollection 2023 Nov.
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Giant Pilomatrix Carcinoma of the Thorax: An Uncommon and Clinically Misdiagnosed Tumor.胸部巨大毛母质癌:一种罕见且临床易误诊的肿瘤。
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