Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Brachytherapy. 2022 Jan-Feb;21(1):128-137. doi: 10.1016/j.brachy.2021.08.003. Epub 2021 Oct 14.
Brachytherapy has a busy workflow relying on manual steps to ensure accurate delivery of the treatment. Systematic treatment errors have been reported due to faulty equipment, inadequate quality assurance (QA) and applicator commissioning methods. This study describes the use of a novel method, the Iridium Imaging System for QA (IrIS - QA), to automate and improve the applicator commissioning for HDR Ir brachytherapy.
A 3D printed holder attached to an Imaging Panel (IP) has been developed to: (1) acquire a high-definition projection of the applicator using the gamma rays of the Ir source for imaging; (2) Track the source within the applicator verifying in a time-resolved manner the dwell positions and dwell times with a high resolution. Results obtained for two applicator models are described in this manuscript.
IrIS-QA is capable of measuring the dwell times with an accuracy better than 0.1 s and interdwell distances with submillimetre precision. The applicators tested in the study showed good agreement between planned and delivered dwell times and positions, with mean and maximum dwell position deviations below 0.5 mm and 1.3 mm, respectively. Dwell time measurements showed agreement superior to 0.05 s except for the first dwell position for which up to 0.15 s differences were observed.
IrIS-QA is a compact system that includes many features necessary to improve the accuracy and efficiency of applicator commissioning and daily QA. No commercial system exists with similar capabilities. IrIS-QA is intended to replace current clinical procedures using film dosimetry.
近距离放射疗法的工作流程繁忙,需要依靠手动步骤来确保治疗的精确实施。由于设备故障、质量保证(QA)不足以及施源器调试方法不当,已经有系统治疗错误的报道。本研究描述了一种新方法,即铱成像系统 QA(IrIS - QA),用于自动化和改进 HDR Ir 近距离放射疗法的施源器调试。
开发了一种 3D 打印固定架,固定在成像板(IP)上,以实现:(1)使用铱源的伽马射线对施源器进行高清晰度的投影成像;(2)在时间分辨的基础上追踪源在施源器内的位置,以高分辨率验证驻留位置和驻留时间。本文描述了对两种施源器模型进行的研究结果。
IrIS-QA 能够以优于 0.1 s 的精度测量驻留时间,以亚毫米精度测量驻留间隔。在研究中测试的施源器显示出计划和交付的驻留时间和位置之间的良好一致性,平均和最大驻留位置偏差分别低于 0.5 毫米和 1.3 毫米。除了第一个驻留位置外,驻留时间测量结果的一致性优于 0.05 s,在第一个驻留位置观察到高达 0.15 s 的差异。
IrIS-QA 是一个紧凑的系统,包含了许多提高施源器调试和日常 QA 精度和效率所需的功能。没有具有类似功能的商业系统。IrIS-QA 旨在取代目前使用胶片剂量学的临床程序。