Rahman M M, Abdullah U S, Joarder A I, Das C, Debnath B C, Sah R
Dr Mohammed Mostafizur Rahman, Associate Professor, Endocrine Surgery, Department of Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Mymensingh Med J. 2017 Jul;26(3):569-573.
Incidental Thyroid Carcinoma (ITC) is quite high as been reported in the world's Journal. This study reviews the frequency of the ITC in patients treated surgically for otherwise benign Thyroid disease in one of the Endocrine surgery unit of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. This study was developed by the investigating the outcome of one hundred and twenty seven patient who underwent partial or total thyroidectomy for benign thyroid pathology in a single Endocrine Surgery Unit of BSMMU from January 2011 to July 2015. This observational study was done to find out the actual incidence of thyroid malignancy among the patients admitted for surgical management with thyroid pathology. All patients underwent at least FNAC and Ultrasonography of the Neck before surgery. Patients with undetermined cytology and follicular nodules were excluded from the study. Overall 19(14.96%) incidental thyroid carcinoma was recorded. Among the ITC 11(8.66%) Papillary Carcinoma, 7(5.51%) Follicular Carcinoma & 1(0.79%) is poorly differentiated carcinoma. The Overall incidence of papillary carcinoma is higher among the incidental carcinoma of Thyroid. Increased incidence associated with follicular adenoma present as an isolated thyroid nodules or multifocal lesion and should be considered malignant potential and total thyroidectomy would be the right choice as surgical management of the both cases. In case of multinodular goiter, total thyroidectomy is currently practiced in majority of the centers and our observations reinforced the attitude further.
据世界期刊报道，偶然甲状腺癌（ITC）的发生率相当高。本研究回顾了在孟加拉国达卡的班加班杜·谢赫·穆吉布医科大学（BSMMU）的一个内分泌外科单元，因其他良性甲状腺疾病接受手术治疗的患者中ITC的发生率。本研究通过调查2011年1月至2015年7月期间在BSMMU的一个内分泌外科单元因良性甲状腺病变接受部分或全甲状腺切除术的127例患者的结果开展。这项观察性研究旨在找出因甲状腺病变入院接受手术治疗的患者中甲状腺恶性肿瘤的实际发生率。所有患者在手术前至少接受了细针穿刺抽吸活检（FNAC）和颈部超声检查。细胞学检查未明确及有滤泡性结节的患者被排除在研究之外。总共记录到19例（14.96%）偶然甲状腺癌。在ITC中，11例（8.66%）为乳头状癌，7例（5.51%）为滤泡状癌，1例（0.79%）为低分化癌。甲状腺偶然癌中乳头状癌的总体发生率较高。与滤泡性腺瘤相关的发生率增加，表现为孤立性甲状腺结节或多灶性病变，应考虑其恶性潜能，全甲状腺切除术将是这两种情况手术治疗的正确选择。对于多结节性甲状腺肿，目前大多数中心都采用全甲状腺切除术，我们的观察进一步强化了这种态度。
