Fernandes Guilherme Arruda, Matos Leandro Luongo de, Dedivitis Rogério Aparecido
Faculdade de Ciências da Saúde, Universidade Metropolitana de Santos, Santos, SP, Brasil.
Surgery Department, Faculdade de Medicina da USP, São Paulo, SP, Brasil.
Int Arch Otorhinolaryngol. 2022 Jun 17;27(1):e138-e142. doi: 10.1055/s-0042-1748925. eCollection 2023 Jan.
The identification of thyroid cancer may be conducted through clinical detection, imaging method, and histopathological examination. Both solitary nodules and multinodular goiter are associated with malignancy. To assess the risk factors for malignancy among patients with multinodular goiter submitted to total thyroidectomy. A series of 712 consecutive patients, submitted to total thyroidectomy between 2005 and 2016 with multinodular goiter regarding clinical, ultrasound, and pathological variables, was retrospectively evaluated. There were 408 cases of papillary carcinoma (57.3%), with the remaining being benign. Gender had no statistical significance ( = 0.169) for malignancy, unlike the Bethesda index, higher age group ( = 0.005), shorter clinical history time ( = 0.036), smaller number of nodules ( < 0.0001), and smaller nodule size ( < 0.0001), which were related to malignancy. The Bethesda index, older age group, shorter clinical history, smaller number of nodules, and smaller size of nodule were related to the diagnosis of papillary carcinoma.
甲状腺癌的识别可通过临床检测、影像学方法和组织病理学检查来进行。单发结节和结节性甲状腺肿均与恶性肿瘤有关。
评估接受甲状腺全切除术的结节性甲状腺肿患者发生恶性肿瘤的危险因素。
回顾性评估了2005年至2016年间连续接受甲状腺全切除术的712例结节性甲状腺肿患者的临床、超声和病理变量。
有408例乳头状癌（57.3%），其余为良性。性别对恶性肿瘤无统计学意义（P = 0.169），与贝塞斯达指数不同，年龄较大组（P = 0.005）、临床病史时间较短（P = 0.036）、结节数量较少（P < 0.0001）和结节尺寸较小（P < 0.0001）与恶性肿瘤有关。
贝塞斯达指数、年龄较大组、临床病史较短、结节数量较少和结节尺寸较小与乳头状癌的诊断有关。
