Zhao Yanan, Yang Ailin, Tu Pengfei, Hu Zhongdong
Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, No.11 North Third Ring Road, Chaoyang District, Beijing, 100029 China.
Chin Med. 2017 Sep 12;12:26. doi: 10.1186/s13020-017-0149-6. eCollection 2017.
Since the incidence of cancer has been on the rise due to increasing exposure to various carcinogenic factors in recent years, cancer has gradually become the first killer to the health of human beings. A growing attention has been paid to anti-cancer effects of traditional Chinese medicine (TCM) with low toxicity and good efficacy. As a kind of TCM, () has a good effect on clinical application, and its anti-tumor effects has been increasingly well studied. In this review, the research progress on the anti-tumor effects of was summarized. The main mechanisms of its anti-tumor effects include suppression of tumor cell growth, induction of cell cycle arrest and tumor cell apoptosis, inhibition of angiogenesis, enhancement of immunity, and reversal of tumor drug resistance. This review aims to provide an overview of the research on anti-tumor effects of and aids in its further application as an anti-tumor drug.
近年来，由于接触各种致癌因素的增加，癌症发病率一直在上升，癌症已逐渐成为人类健康的头号杀手。毒性低、疗效好的中药抗癌作用越来越受到关注。作为一种中药，（）在临床应用中有良好效果，其抗肿瘤作用也得到了越来越深入的研究。本文综述了（）抗肿瘤作用的研究进展。其抗肿瘤作用的主要机制包括抑制肿瘤细胞生长、诱导细胞周期阻滞和肿瘤细胞凋亡、抑制血管生成、增强免疫力以及逆转肿瘤耐药性。本文旨在概述（）抗肿瘤作用的研究，并有助于其作为抗肿瘤药物的进一步应用。
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