Department of Neurology, University of California San Francisco, CA, USA.
Verily Life Sciences, Mountain View, CA, USA.
J Parkinsons Dis. 2017;7(4):755-759. doi: 10.3233/JPD-160929.
We demonstrate the feasibility of estimating clinical tremor scores using an eating utensil with motion-sensing and tremor-cancellation technology in thirteen patients with tremor. Three experts scored hand tremor using the modified Fahn- Tolosa-Marin (FTM) scale. A linear model was trained to estimate tremor severity using the recorded motion signals. The average neurologist FTM score was 1.6±0.7 for PD and 2.6±0.7 for ET patients. The average model score was 1.6±0.7 for PD and 2.6±0.6 for ET. Correlation coefficient between the clinical and model tremor scores was 0.91 (p < 0.001). Motion data from an instrumented eating utensil accurately derived tremor ratings enabling practical, objective daily monitoring.
我们展示了使用具有运动感应和震颤消除技术的餐具来估算震颤临床评分的可行性，该研究共纳入了 13 名震颤患者。三位专家使用改良的 Fahn-Tolosa-Marin（FTM）量表对手部震颤进行评分。使用记录的运动信号训练线性模型来估算震颤严重程度。平均神经科医生 FTM 评分在 PD 患者中为 1.6±0.7，在 ET 患者中为 2.6±0.7。平均模型评分在 PD 患者中为 1.6±0.7，在 ET 患者中为 2.6±0.6。临床和模型震颤评分之间的相关系数为 0.91（p < 0.001）。仪器化餐具的运动数据准确得出震颤评分，从而实现了实际的、客观的日常监测。
