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[法恩-托洛萨-马林特发性震颤量表西班牙语版本的验证研究]

[Validation study of the Spanish version of the Fahn-Tolosa-Marin scale for essential tremor].

作者信息

Castrillo-Fraile M V, Casas-Pena E, Trejo-Gabriel Y Galan J M, Cubo E

机构信息

Hospital Universitario de Burgos, Burgos, Espana.

Universidad de Valladolid, Valladolid, Espana.

出版信息

Rev Neurol. 2019 Oct 1;69(7):265-270. doi: 10.33588/rn.6907.2019067.

DOI:10.33588/rn.6907.2019067
PMID:31559624
Abstract

INTRODUCTION

The Fahn-Tolosa-Marin (FTM) tremor rating scale has been widely used in clinics for the estimation of tremor severity. However, a Spanish language version of this scale has still not been formally validated.

AIM

To provide support to the validity and reliability of this version of FTM Scale.

PATIENTS AND METHODS

A cross-sectional study was conducted on essential tremor patients. Severity was rated using the FTM scale. Upper limb disability was evaluated by terms of Disabilities of the Arm, Shoulder and Hand Scale (DASH), and to health-related quality of life using the Short Form-36 Health Survey (SF-36). Statistical analysis included sample description, reliability (Cronbach's alpha), convergent validity, and discrimination capacity tests (ROC curves).

RESULTS

Forty patients with essential tremor (22 women, 18 men) were included, with a mean age of 65.8 ± 14.7 years (range: 21-90 years). Internal consistency of the FTM was high: Cronbach's alpha: 0,90 (subscale A: 0.85; subscale B: 0.91; subscale C: 0.77), and the floor and ceiling effects were negligible. The FTM (subscale C) showed high correlations with DASH, and acceptable diagnostic capacity, with an area under the curve of 0.86 (95% CI: 0.67-1.00), sensitivity 78% and specificity 75% for a cut-off score > 5.5.

CONCLUSION

The Spanish version of FTM the rating scale is a reliable and valid tool to evaluate disability in patients with essential tremor, and a suitable instrument for use in medical research, as well as in clinical practice.

摘要

引言

法恩-托洛萨-马林(FTM)震颤评定量表已在临床上广泛用于评估震颤严重程度。然而,该量表的西班牙语版本尚未得到正式验证。

目的

为该版本的FTM量表的有效性和可靠性提供支持。

患者与方法

对特发性震颤患者进行了一项横断面研究。使用FTM量表对严重程度进行评分。通过手臂、肩部和手部功能障碍量表(DASH)评估上肢残疾情况,并使用简短36项健康调查(SF-36)评估与健康相关的生活质量。统计分析包括样本描述、信度(克朗巴哈系数)、收敛效度和区分能力测试(ROC曲线)。

结果

纳入40例特发性震颤患者(22例女性,18例男性),平均年龄65.8±14.7岁(范围:21-90岁)。FTM的内部一致性较高:克朗巴哈系数为0.90(子量表A:0.85;子量表B:0.91;子量表C:0.77),地板效应和天花板效应可忽略不计。FTM(子量表C)与DASH显示出高度相关性,诊断能力可接受,曲线下面积为0.86(95%CI:0.67-1.00),截断分数>5.5时,敏感性为78%,特异性为75%。

结论

FTM评定量表的西班牙语版本是评估特发性震颤患者残疾情况的可靠且有效的工具,是适用于医学研究以及临床实践的合适工具。

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