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GlyTouCan:一个易于访问的聚糖结构知识库。

GlyTouCan: an accessible glycan structure repository.

机构信息

Complex Carbohydrate Research Center, The University of Georgia, 315 Riverbend Rd, Athens, Georgia 30602, USA.

The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.

出版信息

Glycobiology. 2017 Oct 1;27(10):915-919. doi: 10.1093/glycob/cwx066.

Abstract

Rapid and continued growth in the generation of glycomic data has revealed the need for enhanced development of basic infrastructure for presenting and interpreting these datasets in a manner that engages the broader biomedical research community. Early in their growth, the genomic and proteomic fields implemented mechanisms for assigning unique gene and protein identifiers that were essential for organizing data presentation and for enhancing bioinformatic approaches to extracting knowledge. Similar unique identifiers are currently absent from glycomic data. In order to facilitate continued growth and expanded accessibility of glycomic data, the authors strongly encourage the glycomics community to coordinate the submission of their glycan structures to the GlyTouCan Repository and to make use of GlyTouCan identifiers in their communications and publications. The authors also deeply encourage journals to recommend a submission workflow in which submitted publications utilize GlyTouCan identifiers as a standard reference for explicitly describing glycan structures cited in manuscripts.

摘要

糖组学数据的快速持续增长揭示了需要加强基本基础设施的开发,以便以吸引更广泛的生物医学研究界参与的方式呈现和解释这些数据集。在其发展的早期,基因组学和蛋白质组学领域实施了分配独特基因和蛋白质标识符的机制,这对于组织数据呈现和增强生物信息学方法提取知识至关重要。类似的独特标识符目前在糖组学数据中不存在。为了促进糖组学数据的持续增长和扩大可及性,作者强烈鼓励糖组学社区协调将其聚糖结构提交到 GlyTouCan 存储库,并在他们的交流和出版物中使用 GlyTouCan 标识符。作者还强烈鼓励期刊推荐提交工作流程,其中提交的出版物将 GlyTouCan 标识符用作明确描述手稿中引用的聚糖结构的标准参考。

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本文引用的文献

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