Graduate School of Science and Engineering, Soka University, Tokyo 192-8577, Japan.
The Noguchi Institute, Tokyo 173-0003, Japan.
Nucleic Acids Res. 2021 Jan 8;49(D1):D1529-D1533. doi: 10.1093/nar/gkaa947.
Glycans serve important roles in signaling events and cell-cell communication, and they are recognized by lectins, viruses and bacteria, playing a variety of roles in many biological processes. However, there was no system to organize the plethora of glycan-related data in the literature. Thus GlyTouCan (https://glytoucan.org) was developed as the international glycan repository, allowing researchers to assign accession numbers to glycans. This also aided in the integration of glycan data across various databases. GlyTouCan assigns accession numbers to glycans which are defined as sets of monosaccharides, which may or may not be characterized with linkage information. GlyTouCan was developed to be able to recognize any level of ambiguity in glycans and uniquely assign accession numbers to each of them, regardless of the input text format. In this manuscript, we describe the latest update to GlyTouCan in version 3.0, its usage, and plans for future development.
糖链在信号事件和细胞间通讯中发挥着重要作用，它们被凝集素、病毒和细菌识别，在许多生物过程中发挥着多种作用。然而，文献中没有系统地组织大量的糖链相关数据。因此，GlyTouCan（https://glytoucan.org）被开发为国际糖链数据库，允许研究人员为糖链分配访问号。这也有助于整合来自不同数据库的糖链数据。GlyTouCan 为糖链分配访问号，这些糖链被定义为一组单糖，可能具有或不具有连接信息的特征。GlyTouCan 的开发目的是能够识别糖链中的任何程度的模糊性，并为每个糖链唯一地分配访问号，而不考虑输入文本的格式。在本文中，我们描述了 GlyTouCan 在版本 3.0 中的最新更新、它的用法以及未来的发展计划。
