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一名早产男婴的侵袭性早产儿视网膜病变

Aggressive Posterior Retinopathy of Prematurity in a Premature Male Infant.

作者信息

Zhou Jun, Liu Zheng, Ying Hai-Yan, Liu Tao

机构信息

Department of Ophthalmology, 3201 Hospital, Xi'an Jiaotong University Health Science Center, Hanzhong, China.

Department of Pathology and Molecular Medicine, 3201 Hospital, Xi'an Jiaotong University Health Science Center, Hanzhong, China.

出版信息

Case Rep Ophthalmol. 2017 Jul 25;8(2):396-400. doi: 10.1159/000478694. eCollection 2017 May-Aug.

DOI:10.1159/000478694
PMID:28924435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5597914/
Abstract

A premature male infant was born at 30 weeks' gestation with a birth weight of 1,700 g in a rural hospital. He was diagnosed with respiratory distress syndrome and received continuous positive airway pressure treatment for 26 days. At 26 days after birth, the patient was transferred to our hospital for further evaluation and management. A comprehensive eye examination revealed a stage 3 retinopathy of prematurity (ROP) involving zone 2 in both eyes. The patient was recommended to a provincial-level eye hospital for emergency laser therapy. Five months after birth, the feedback from the eye hospital showed that the patient had a high risk of blindness in both eyes. Our case report shows that delaying first screening examination increases the possibility of developing aggressive posterior ROP in infants with ROP. Doctors in rural hospitals should be aware of this possibility and trained for early screening and treatment in high-risk infants.

摘要

一名早产男婴在一家乡村医院孕30周时出生,出生体重1700克。他被诊断为呼吸窘迫综合征,并接受了持续气道正压通气治疗26天。出生后26天,该患者被转至我院进行进一步评估和治疗。全面的眼部检查显示双眼为3期早产儿视网膜病变(ROP),累及2区。该患者被转诊至省级眼科医院进行紧急激光治疗。出生五个月后,眼科医院的反馈显示该患者双眼失明风险很高。我们的病例报告表明,推迟首次筛查检查会增加ROP婴儿发生侵袭性后部ROP的可能性。乡村医院的医生应意识到这种可能性,并接受高危婴儿早期筛查和治疗的培训。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731b/5597914/1c826ebfca97/cop-0008-0396-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731b/5597914/0fd081fa1aca/cop-0008-0396-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731b/5597914/1c826ebfca97/cop-0008-0396-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731b/5597914/0fd081fa1aca/cop-0008-0396-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/731b/5597914/1c826ebfca97/cop-0008-0396-g02.jpg

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Med Sci Monit. 2016 Apr 10;22:1192-209. doi: 10.12659/msm.897095.
2
Retinopathy of prematurity: Past, present and future.早产儿视网膜病变:过去、现在与未来。
World J Clin Pediatr. 2016 Feb 8;5(1):35-46. doi: 10.5409/wjcp.v5.i1.35.
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Screening for retinopathy of prematurity in China: a neonatal units-based prospective study.
局部应用辅酶Q10和维生素E滴眼液治疗早产儿视网膜病变的临床疗效
Med Hypothesis Discov Innov Ophthalmol. 2019 Winter;8(4):291-297. Epub 2019 Oct 1.
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The safety and effectiveness of 0.16 mg bevacizumab plus or minus additional laser photocoagulation in the treatment of retinopathy of prematurity.0.16mg 贝伐单抗联合或不联合额外激光光凝治疗早产儿视网膜病变的安全性和有效性。
Indian J Ophthalmol. 2019 Jun;67(6):879-883. doi: 10.4103/ijo.IJO_2115_18.
中国早产儿视网膜病变筛查:一项基于新生儿病房的前瞻性研究。
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