Aghighi M, Mahdavi-Mazdeh M, Saberi Isfeedvajani M, Tavakoli S A, Tirgar N, Heidary Rouchi A
Iranian Tissue Bank and Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Int J Organ Transplant Med. 2017;8(3):165-167. Epub 2017 Aug 1.
Regardless of the level of development, religion and beliefs have crucial impact on people's attitude towards organ donation. Although organ donation in Islam is obviously appraised, mainly due to lack of an appropriate infrastructure, post-mortem donation rate in Islamic countries is not comparable to successful settings. We conducted this study to assess the extent of contribution of factors that reduce the level of effectiveness, and also to determine the impact of altruistic feelings in the month of Ramadan on family refusal as the leading modifiable contributor to organ donation rate. All records of potential and actual brain-dead donors, referred to Organ Procurement Unit of the Iranian Tissue Bank, from January 1, 2005 to December 31, 2014, were analyzed. In each year, the number of potential and actual donors in the month of Ramadan was compared to the mean value in the remaining 11 months. Of 1758 total potential donors in 10 years, 464 cases became actual donors (26.4% as overall level of effectiveness). The reasons for non-effectiveness were medical contraindications (25.4%), cardiac arrest before referral or during maintenance (7.4%), family refusal (30.8%), judicial refusal (8.7%), (1.3%). Analysis showed no significant differences between donation rates (both potential and actual) in Ramadan and non-Ramadan months for potential (Δ=3.55, 95% CI: -6.7 to 13.8) and actual donors (Δ=1.35, 95% CI: -2.3 to 5). Despite the undeniable role of religion and beliefs in the establishment of organ procurement program from brain-dead donors, there was no monthly variability in post-mortem organ donation rate.
无论发展水平如何，宗教和信仰对人们对器官捐赠的态度都有着至关重要的影响。尽管伊斯兰教对器官捐赠明显持赞赏态度，但主要由于缺乏适当的基础设施，伊斯兰国家的尸检捐赠率与成功案例不可相提并论。我们开展这项研究，以评估降低有效性水平的因素的影响程度，并确定斋月期间利他情感对作为器官捐赠率主要可改变因素的家庭拒绝的影响。分析了2005年1月1日至2014年12月31日期间转诊至伊朗组织库器官采购单位的潜在和实际脑死亡捐赠者的所有记录。每年将斋月期间潜在和实际捐赠者的数量与其余11个月的平均值进行比较。在10年的1758名潜在捐赠者中，有464例成为实际捐赠者（总体有效率为26.4%）。无效的原因包括医学禁忌（25.4%）、转诊前或维持期间心脏骤停（7.4%）。家庭拒绝（30.8%）、司法拒绝（8.7%）、（1.3%）。分析表明，斋月和非斋月期间潜在捐赠者（Δ=3.55，95%CI：-6.7至13.8）和实际捐赠者（Δ=1.35，95%CI：-2.3至5）的捐赠率没有显著差异。尽管宗教和信仰在建立脑死亡捐赠者器官采购计划中有着不可否认的作用，但尸检器官捐赠率没有月度变化。
