Baker A R, Neoptolemos J P, Leese T, James D C, Fossard D P
Department of Surgery, Leicester Royal Infirmary.
Ann R Coll Surg Engl. 1987 Nov;69(6):253-7.
From a consecutive series of 190 patients with choledochoduodenostomy (CDD) and 56 patients with transduodenal sphincteroplasty (TDS), there were 10 and 3 hospital deaths respectively. A long term follow-up study was performed on the remainder. Late deaths occurred in 35 CDD and 5 TDS patients. Serious long term complications occurred in 3.3% of CDD cases, comprising 5 cases of 'sump syndrome' and a further case of cholangitis in the presence of a clear biliary tree. Cholangitis occurred in 2 of the TDS patients (3.8%). Recurrent common duct stones were found in 3 of the 'sump syndrome' cases (1.6%) and one of the TDS patients with cholangitis (1.9%). Eighty-eight per cent of the CDD patients and 90.2% of the TDS patients, who were reviewed, were subjectively well. Serum alkaline phosphatase was raised in 21.6% of the CDD patients and only 3.4% of the TDS group (P less than 0.05). Radiological studies showed that the CDD stoma admitted air and barium more often than the TDS stoma (P less than 0.001). Neither the biochemical nor the radiological findings correlated with the long term symptomatic results of the two procedures. Dynamic HIDA scans showed a shorter time to peak activity in the common hepatic duct for both CDD (P less than 0.01) and TDS (P less than 0.05) as compared with endoscopic sphincterotomy (ES). These long-term clinical, biochemical and radiological results are similar to those reported following ES.
在连续的190例胆总管十二指肠吻合术(CDD)患者和56例经十二指肠括约肌成形术(TDS)患者中,分别有10例和3例医院死亡病例。对其余患者进行了长期随访研究。CDD组有35例患者和TDS组有5例患者出现晚期死亡。CDD病例中有3.3%发生了严重的长期并发症,包括5例“贮袋综合征”以及1例在胆管树清晰情况下发生的胆管炎。TDS患者中有2例(3.8%)发生胆管炎。在3例“贮袋综合征”病例(1.6%)和1例发生胆管炎的TDS患者(1.9%)中发现了复发性胆总管结石。接受复查的CDD患者中有88%和TDS患者中有90.2%主观感觉良好。CDD患者中有21.6%血清碱性磷酸酶升高,而TDS组仅为3.4%(P<0.05)。放射学研究表明,CDD吻合口比TDS吻合口更常允许空气和钡剂通过(P<0.001)。生化和放射学检查结果均与这两种手术的长期症状结果无关。动态HIDA扫描显示,与内镜下括约肌切开术(ES)相比,CDD(P<0.01)和TDS(P<0.05)患者肝总管达到峰值活性的时间更短。这些长期的临床、生化和放射学结果与ES术后报道的结果相似。