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Diagnosis and management of schwannomas originating from the cervical vagus nerve.起源于颈段迷走神经的神经鞘瘤的诊断与治疗
Ann R Coll Surg Engl. 2015 Mar;97(2):92-7. doi: 10.1308/003588414X14055925058355.
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Parapharyngeal space tumours: the efficiency of a transcervical approach without mandibulotomy through review of 44 cases.咽旁间隙肿瘤:经颈入路不进行下颌骨切开术的有效性——44例病例回顾
Acta Otorhinolaryngol Ital. 2014 Oct;34(5):310-6.
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Management of tumors arising from the parapharyngeal space: A systematic review of 1,293 cases reported over 25 years.咽旁间隙肿瘤的管理:对25年间报告的1293例病例的系统评价
Laryngoscope. 2015 Jun;125(6):1372-81. doi: 10.1002/lary.25077. Epub 2014 Dec 2.
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Schwannoma of the median nerve: diagnosis sometimes delayed.正中神经鞘瘤:诊断有时会延迟。
Clin Med Insights Case Rep. 2014 Jul 29;7:71-3. doi: 10.4137/CCRep.S16686. eCollection 2014.
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Primary parapharyngeal tumours: a review of 21 cases.原发性咽旁肿瘤:21例病例回顾
Oral Maxillofac Surg. 2014 Sep;18(3):283-92. doi: 10.1007/s10006-014-0451-8. Epub 2014 Apr 24.
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The transcervical approach for parapharyngeal space pleomorphic adenomas: indications and technique.经颈入路治疗咽旁间隙多形性腺瘤:适应证与技术
PLoS One. 2014 Feb 27;9(2):e90210. doi: 10.1371/journal.pone.0090210. eCollection 2014.
7
Transoral robotic surgery of the parapharyngeal space: a case series and systematic review.经口机器人手术治疗咽旁间隙疾病:病例系列与系统评价
Head Neck. 2015 Feb;37(2):293-8. doi: 10.1002/hed.23557. Epub 2014 Mar 13.
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Diagnosis and management of extracranial head and neck schwannomas: a review of 27 cases.颅外头颈部神经鞘瘤的诊断与治疗:27例病例回顾
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9
Radiographic association of schwannomas with sensory ganglia.神经鞘瘤与感觉神经节的放射学关联。
Otol Neurotol. 2012 Sep;33(7):1276-82. doi: 10.1097/MAO.0b013e318263d315.
10
Diagnostic accuracy and safety of fine-needle aspiration biopsy of the parapharyngeal space.咽旁间隙细针穿刺活检的诊断准确性及安全性
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咽旁间隙肿瘤的外科治疗:29例报告

Surgical treatment of parapharyngeal space tumors: A report of 29 cases.

作者信息

Ijichi Kei, Murakami Shingo

机构信息

Department of Otolaryngology-Head and Neck Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467-8601, Japan.

出版信息

Oncol Lett. 2017 Sep;14(3):3249-3254. doi: 10.3892/ol.2017.6480. Epub 2017 Jun 23.

DOI:10.3892/ol.2017.6480
PMID:28927073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5588032/
Abstract

The present study aimed to establish a strategy for parapharyngeal space (PPS) tumor surgery based on preoperative symptoms, clinical signs, imaging and histological examination. A retrospective cohort study was conducted with 29 adult patients who underwent surgery for primary PPS tumors from 2008-2015. The following data was obtained: Preoperative symptoms of the patient, histological type of the tumor, surgical approach and complications. Of the 29 patients who underwent surgery to remove a PPS tumor, 16 presented with neurogenic tumors and 13 with salivary gland tumors. The most common symptom was the presence of a neck mass. Preoperative computed tomography and magnetic resonance imaging were performed to evaluate the size and location of the tumors. The majority of the salivary gland tumors were located in the prestyloid space, whereas all neurogenic tumor cases were poststyloid. A total of 21 of the 29 patients (72.4%) underwent a preoperative fine needle aspiration (FNAC) examination. FNAC contributed to preoperative diagnosis in 9 of these cases (42.9%). In parotid tumors of the prestyloid space, facial nerve palsy was a common postoperative complication. In the case of neurogenic tumors, a common complication was the postoperative palsy of the nerve of tumor origin. The strategy for PPS surgery, from the preoperative diagnosis to the operative method, remains controversial. The data on pre- and postoperative symptoms, imaging and histological diagnosis, and the selection of surgical method depending on a neurogenic or salivary tumor origin in the present study indicated that improving the method of examination, carefully selecting the method of approach and accurately managing surgery leads to complete tumor removal, and that the use of nerve-preserving techniques may reduce the likelihood of complications.

摘要

本研究旨在基于术前症状、临床体征、影像学及组织学检查,制定一项咽旁间隙(PPS)肿瘤手术策略。对29例2008年至2015年接受原发性PPS肿瘤手术的成年患者进行了一项回顾性队列研究。获取了以下数据:患者的术前症状、肿瘤的组织学类型、手术入路及并发症。在29例行PPS肿瘤切除手术的患者中,16例为神经源性肿瘤,13例为涎腺肿瘤。最常见的症状是颈部肿块。术前行计算机断层扫描和磁共振成像以评估肿瘤的大小和位置。大多数涎腺肿瘤位于茎突前间隙,而所有神经源性肿瘤病例均位于茎突后。29例患者中有21例(72.4%)术前行细针穿刺抽吸(FNAC)检查。其中9例(42.9%)FNAC有助于术前诊断。在茎突前间隙的腮腺肿瘤中,面神经麻痹是常见的术后并发症。对于神经源性肿瘤,常见并发症是肿瘤起源神经的术后麻痹。从术前诊断到手术方法,PPS手术策略仍存在争议。本研究中关于术前和术后症状、影像学及组织学诊断,以及根据神经源性或涎腺肿瘤起源选择手术方法的数据表明,改进检查方法、谨慎选择入路方法及精确管理手术可实现肿瘤的完整切除,并且使用保留神经技术可能会降低并发症的发生率。