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颅外头颈部神经鞘瘤:97例单中心回顾性研究经验

Extracranial Head and Neck Schwannomas: A Single Centre Retrospective Experience of 97 Cases.

作者信息

Verma Prankur, Riju Jeyashanth, Ramalingam Natarajan, Zeinuddeen Rubine, Paulose Antony Abraham, Susheel Sherin, Thomas Meera, Sundaresan Rajan, Michael Rajiv, Tirkey Amit Jiwan, Irodi Aparna, Kiranmayi C

机构信息

Department of Head and Neck Surgery, Christian Medical College, Vellore, Tamil Nadu 632002 India.

Department of Pathology, Christian Medical College, Vellore, Tamil Nadu 632002 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4292-4299. doi: 10.1007/s12070-024-04839-w. Epub 2024 Jul 2.

Abstract

INTRODUCTION

Schwannomas are rare benign neurogenic tumours. About 25-45% of extracranial schwannomas are found in the head and neck region. In the head and neck, they can arise from various cranial, peripheral and autonomic nerves. Due to this, they have varied clinical presentations.

MATERIAL AND METHODS

This retrospective cohort includes 97 patients diagnosed with extra cranial head and neck schwannoma, and operated in the Otolaryngology and Head & Neck Surgery department, from 2013 to 2022. The parameters observed were the age and gender distribution, location, nerve of origin, size, pressure symptoms, cranial palsies, post-operative symptoms, recurrence and complications. The data were collected from the institute's electronic records.

RESULTS

The median age of the study population was 36 years; among them, 51 were men and 46 were women. The most common tumour location was parapharynx. The patients had varied head and neck symptoms, of which 23.7% had nerve paresis at presentation. Transcervical surgical approaches was most used. New onset cranial nerve paresis immediately post-surgery was noted in 22.7%. Recurrence was noted in 2% of cases.

CONCLUSIONS

Extra cranial schwannomas are uncommon neoplasms and have varied presentations. Comprehensive evaluation with appropriate imaging should be done in all cases. Though benign, patients can present with nerve paresis. Recurrence is uncommon after complete resection.

摘要

引言

施万细胞瘤是罕见的良性神经源性肿瘤。约25%-45%的颅外施万细胞瘤发生于头颈部区域。在头颈部,它们可起源于各种颅神经、周围神经和自主神经。因此,它们有多种临床表现。

材料与方法

这项回顾性队列研究纳入了97例2013年至2022年期间在耳鼻咽喉头颈外科诊断为颅外头颈部施万细胞瘤并接受手术治疗的患者。观察的参数包括年龄和性别分布、位置、起源神经、大小、压迫症状、颅神经麻痹、术后症状、复发和并发症。数据从该机构的电子记录中收集。

结果

研究人群的中位年龄为36岁;其中,男性51例,女性46例。最常见的肿瘤位置是咽旁。患者有多种头颈部症状,其中23.7%在就诊时存在神经麻痹。最常采用经颈手术入路。术后立即出现新发颅神经麻痹的比例为22.7%。2%的病例出现复发。

结论

颅外施万细胞瘤是罕见肿瘤,有多种表现形式。所有病例均应进行适当影像学检查的综合评估。虽然是良性肿瘤,但患者可能出现神经麻痹。完整切除后复发罕见。

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