Eye Center at the Medical Center and Faculty of Medicine of the University of Freiburg; Institute for Ophthalmic Research, Section for Neurobiology of the Eye, University of Tübingen.
Dtsch Arztebl Int. 2017 Sep 4;114(35-36):575-580. doi: 10.3238/arztebl.2017.0575.
Nearsightedness (myopia) has become more common around the world recently, mainly because of changes in visual, educational, and recreational behavior. The question arises how the risk of myopia and its progression can be reduced. This would lessen the prevalence and severity of myopia and also lower the risk of secondary diseases that impair visual acuity.
The PubMed/Medline database was selectively searched for pertinent literature.
The risk of myopia is lowered by exposure to daylight and increased by activities performed at short visual distances (close-up work). A person with little exposure to daylight has a fivefold risk of developing myopia, which can rise as high as a 16-fold risk if that person also performs close-up work. Two meta-analyses and a large randomized clinical trial from Asia have shown that the progression of myopia over two years of observation can be lessened by up to 0.71 diopters by the administration of atropine eye drops in a concentration that has practically no serious side effects. At higher doses, myopia progresses more severely than in the placebo group after the cessation of therapy. This is an off-label treatment. A weaker effect on progression has been shown for multifocal optical corrections that include both a distance correction and a correction for near vision.
Effective pharmacological and optical measures are now available to lessen the progression of myopia. The increasing prevalence of myopia should motivate pediatricians, parents, and schools to pay attention to risk factors such as close-up work and lack of daylight exposure, particularly in view of the increased use of digital media.
近年来,近视(近视)在世界各地变得越来越普遍,主要是由于视觉、教育和娱乐行为的改变。问题是如何降低近视的风险及其进展。这将降低近视的流行率和严重程度,也降低损害视力的继发性疾病的风险。
选择性地在 PubMed/Medline 数据库中搜索相关文献。
暴露在日光下可降低近视的风险,而进行短距离视觉活动(近距离工作)则会增加近视的风险。一个很少暴露在日光下的人患近视的风险是五倍,如果这个人还从事近距离工作,近视的风险可能高达 16 倍。两项来自亚洲的荟萃分析和一项大型随机临床试验表明,通过使用浓度实际上没有严重副作用的阿托品眼药水,可以将两年观察期间近视的进展减少多达 0.71 屈光度。在停止治疗后,高剂量的近视进展比安慰剂组更严重。这是一种标签外的治疗方法。多焦点光学矫正对进展的影响较弱,包括远距矫正和近距矫正。
目前有有效的药物和光学措施可以减缓近视的进展。近视患病率的增加应促使儿科医生、家长和学校关注近距离工作和缺乏日光暴露等危险因素,特别是考虑到数字媒体使用的增加。