Goh Brian K P, Lee Ser-Yee, Kam Juinn-Huar, Soh Hui Ling, Cheow Peng-Chung, Chow Pierce K H, Ooi London L P J, Chung Alexander Y F, Chan Chung-Yip
Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 169856, Singapore.
J Minim Access Surg. 2018 Apr-Jun;14(2):140-145. doi: 10.4103/jmas.JMAS_26_17.
This study aims to study the changing trends and outcomes associated with the adoption of minimally invasive distal pancreatectomy (MIDP) at a single centre.
Retrospective review of sixty consecutive patients who underwent MIDP from September 2006 to November 2016 at a single institution. To study the evolution of MIDP, the study population was divided into three groups consisting of twenty patients (Group I, Group II and Group III).
Sixty patients underwent MIDP with 11 (18.3%) requiring open conversions. The median operation time was 305 (range: 85-775) min and the median post-operative stay was 6 (range: 3-73) days. Fifteen procedures were spleen-saving pancreatectomies. Major post-operative morbidity (>Grade 2) occurred in 12 (20.0%) patients and there was no mortality or reoperations. There were 33 (55.0%) pancreatic fistulas, of which 15 (25.0%) were Grade B fistulas of which 12 (20.0%) required percutaneous drainage. Comparison between the three groups demonstrated a statistically significant increase in the frequency of procedures performed, increase in robotic-assisted procedures and proportion of asymptomatic tumours resected. There also tended to be non-significant decrease in open conversion rates from 25% to 5% between the three groups and increase in tumour size resected from 24 to 40 mm.
Comparison between the three groups demonstrated that MIDP was performed with increased frequency. There was a statistically significant increase in the frequency of resections performed for asymptomatic tumours and resections performed through robotic assistance. There was also a non-significant trend towards a decrease in open conversions and increase in the size of tumours resected.
本研究旨在探讨在单一中心采用微创远端胰腺切除术(MIDP)的变化趋势及结果。
回顾性分析2006年9月至2016年11月在单一机构连续接受MIDP的60例患者。为研究MIDP的发展演变,将研究人群分为三组,每组20例患者(第一组、第二组和第三组)。
60例患者接受了MIDP,其中11例(18.3%)需要转为开放手术。中位手术时间为305(范围:85 - 775)分钟,中位术后住院时间为6(范围:3 - 73)天。15例手术为保留脾脏的胰腺切除术。12例(20.0%)患者发生了严重术后并发症(>2级),无死亡或再次手术情况。发生了33例(55.0%)胰瘘,其中15例(25.0%)为B级胰瘘,12例(20.0%)需要经皮引流。三组之间的比较显示,手术操作频率有统计学意义的增加,机器人辅助手术增加,无症状肿瘤切除比例增加。三组之间开放手术转换率也有从25%降至5%的非显著性下降趋势,切除肿瘤大小从24毫米增加到40毫米。
三组之间的比较表明,MIDP的实施频率有所增加。无症状肿瘤切除频率和机器人辅助切除频率有统计学意义的增加。开放手术转换率也有非显著性下降趋势,切除肿瘤大小增加。