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脊髓损伤患者中表现为自主神经反射异常的心血管功能障碍

Cardiovascular Dysfunction Presenting as Autonomic Dysreflexia in a Patient with Spinal Cord Injury.

作者信息

Qavi Ahmed H, Assad Salman, Shabbir Wardha, Kundi Maryam, Habib Maham, Babar Sumbal, Zahid Mehr

机构信息

Department of Medicine, Mahroof Hospital.

Department of Medicine, Shifa International Hospital, Islamabad, Pakistan.

出版信息

Cureus. 2017 Jul 10;9(7):e1456. doi: 10.7759/cureus.1456.

DOI:10.7759/cureus.1456
PMID:28929040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5590769/
Abstract

Autonomic dysreflexia (AD) is a medical emergency that is characterized by hypertension as an autonomic response to noxious stimuli in patients with a history of spinal cord injury at the level of T6 or above. We present the case of a 31-year-old Caucasian male with a history of spinal cord injury at the level of C3-C4, with symptoms described as recurring episodes of hypertension with flushing and sweating above the level of the lesion for the past five to six years. His symptoms are triggered by bowel distention, excitement, a bumpy car ride, or a simple turning of the neck to the left. Physical examination and laboratory studies ruled out other possible differentials (e.g., migraines, pheochromocytoma). As a result, AD was diagnosed.

摘要

自主神经反射异常(AD)是一种医疗急症,其特征为高血压,这是T6及以上脊髓损伤患者对有害刺激的自主神经反应。我们报告一例31岁的白种男性病例,其脊髓损伤平面为C3 - C4,在过去五到六年中出现过反复的高血压发作,并伴有损伤平面以上部位的脸红和出汗症状。他的症状由肠道扩张、兴奋、颠簸的乘车过程或简单地向左转头引发。体格检查和实验室检查排除了其他可能的鉴别诊断(如偏头痛、嗜铬细胞瘤)。因此,诊断为自主神经反射异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/5590769/46c005714a8b/cureus-0009-00000001456-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/5590769/46c005714a8b/cureus-0009-00000001456-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f56a/5590769/46c005714a8b/cureus-0009-00000001456-i01.jpg

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本文引用的文献

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Four-rod Instrumentation for Treatment of Charcot Spinal Arthropathy Causing Autonomic Dysreflexia: Case Report and Literature Review.用于治疗导致自主神经反射异常的夏科氏脊柱关节病的四杆器械:病例报告与文献综述
Cureus. 2016 Oct 27;8(10):e850. doi: 10.7759/cureus.850.
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Cardiovascular dysfunction following spinal cord injury.脊髓损伤后的心血管功能障碍。
Neural Regen Res. 2016 Feb;11(2):189-94. doi: 10.4103/1673-5374.177707.
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Autonomic hyperreflexia after spinal cord injury managed successfully with intravenous lidocaine: a case report.
脊髓损伤后静脉注射利多卡因成功治疗自主神经反射亢进:一例报告
Patient Saf Surg. 2016 Mar 15;10:10. doi: 10.1186/s13037-016-0098-5. eCollection 2016.
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Autonomic dysreflexia in acute spinal cord injury: an under-recognized clinical entity.急性脊髓损伤中的自主神经反射异常:一种未得到充分认识的临床病症。
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