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脊髓损伤后静脉注射利多卡因成功治疗自主神经反射亢进:一例报告

Autonomic hyperreflexia after spinal cord injury managed successfully with intravenous lidocaine: a case report.

作者信息

Leão Pedro, Figueiredo Paulo

机构信息

Department of Anesthesiology and Pain Medicine, Centro Hospitalar de Entre o Douro e Vouga, Rua Dr. Cândido Pinho, 4520-211 Santa Maria da Feira, Portugal.

Director of the Department of Anesthesiology and Pain Medicine, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Portugal.

出版信息

Patient Saf Surg. 2016 Mar 15;10:10. doi: 10.1186/s13037-016-0098-5. eCollection 2016.

DOI:10.1186/s13037-016-0098-5
PMID:26985238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4793543/
Abstract

BACKGROUND

Some paraplegic patients may wish undergo some surgical procedures, like urological procedures, without anesthesia. However, these patients can develop autonomic hyperreflexia if cystoscopy is performed without anesthesia.

CASE PRESENTATION

We present a case of severe autonomic hyperreflexia in a 44-year-old male with spinal cord injury at the level of T4 during urologic procedure under sedation and analgesia successfully treated with intravenous lidocaine.

CONCLUSIONS

This case illustrates that patients with spinal cord injuries are likely to develop autonomic hyperreflexia during urological procedures performed without anesthesia. Health professionals should educate spinal cord injury patients regarding risks of this serious condition and be aware to prevent and manage autonomic hyperreflexia. In an acute episode, nifedipine, nitrates and captopril are the most commonly used and recommended agents. To our knowledge, this is the first case report of severe autonomic hyperreflexia treated successfully with intravenous lidocaine.

摘要

背景

一些截瘫患者可能希望在无麻醉的情况下接受某些外科手术,如泌尿外科手术。然而,如果在无麻醉的情况下进行膀胱镜检查,这些患者可能会发生自主神经反射亢进。

病例介绍

我们报告一例44岁男性在镇静镇痛下进行泌尿外科手术时发生严重自主神经反射亢进的病例,该男性在T4水平脊髓损伤,经静脉注射利多卡因成功治疗。

结论

该病例表明,脊髓损伤患者在无麻醉的泌尿外科手术过程中可能会发生自主神经反射亢进。卫生专业人员应向脊髓损伤患者宣传这种严重情况的风险,并注意预防和处理自主神经反射亢进。在急性发作时,硝苯地平、硝酸盐和卡托普利是最常用和推荐的药物。据我们所知,这是首例静脉注射利多卡因成功治疗严重自主神经反射亢进的病例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f252/4793543/cebca637edc3/13037_2016_98_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f252/4793543/36abbc17ca90/13037_2016_98_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f252/4793543/cebca637edc3/13037_2016_98_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f252/4793543/36abbc17ca90/13037_2016_98_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f252/4793543/cebca637edc3/13037_2016_98_Fig2_HTML.jpg

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J Anaesthesiol Clin Pharmacol. 2013 Apr;29(2):241-3. doi: 10.4103/0970-9185.111652.
2
Remifentanil decreases sevoflurane requirements to block autonomic hyperreflexia during transurethral litholapaxy in patients with high complete spinal cord injury.瑞芬太尼降低高位完全性脊髓损伤患者行经尿道膀胱结石碎石术中自主神经反射亢进的七氟醚需求。
Anesth Analg. 2011 Jan;112(1):191-7. doi: 10.1213/ANE.0b013e3181fc7139. Epub 2010 Oct 21.
3
A systematic review of the management of autonomic dysreflexia after spinal cord injury.
脊髓损伤后自主神经反射异常管理的系统评价
Arch Phys Med Rehabil. 2009 Apr;90(4):682-95. doi: 10.1016/j.apmr.2008.10.017.
4
Autonomic dysfunction in spinal cord injury: clinical presentation of symptoms and signs.脊髓损伤中的自主神经功能障碍:症状和体征的临床表现
Prog Brain Res. 2006;152:1-8. doi: 10.1016/S0079-6123(05)52034-X.
5
Autonomic hyperreflexia and its control in patients with spinal cord lesions.脊髓损伤患者的自主神经反射亢进及其控制
Ann Intern Med. 1956 Apr;44(4):678-86. doi: 10.7326/0003-4819-44-4-678.
6
Autonomic dysreflexia in acute spinal cord injury: an under-recognized clinical entity.急性脊髓损伤中的自主神经反射异常:一种未得到充分认识的临床病症。
J Neurotrauma. 2003 Aug;20(8):707-16. doi: 10.1089/089771503767869944.
7
Isobaric spinal anesthesia for paraplegic patients.截瘫患者的等比重脊髓麻醉。
Acta Anaesthesiol Sin. 1999 Mar;37(1):29-34.
8
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9
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Anaesthesia. 1998 Mar;53(3):273-89. doi: 10.1046/j.1365-2044.1998.00337.x.
10
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J Spinal Cord Med. 1997 Jul;20(3):361-4.