Dada Ayokunle S, Ajayi Daisi D, Areo Peter O, Raimi Taiwo H, Emmanuel Eyitayo E, Odu Olusola O, Aremu Olusegun A
Department of Medicine, Ekiti State University Teaching Hospital, Ado Ekiti 36001, Ekiti State, Nigeria.
Department of Medical Laboratory Science, Ekiti State University Teaching Hospital, Ado Ekiti 36001, Ekiti State, Nigeria.
Medicines (Basel). 2016 Jun 9;3(2):15. doi: 10.3390/medicines3020015.
The heightened cardiovascular risk associated with metabolic syndrome (MetS) has been documented by several researchers. The Framingham risk score (FRS) provides a simple and efficient method for identifying individuals at cardiovascular risk. The objective was to describe the prevalence of MetS and its association with FRS in predicting cardiovascular disease among a cohort of semi-urban women; Clinical and laboratory parameters were evaluated among 189 healthy women. The International Diabetes Federation definition was used to diagnose metabolic syndrome. FRS was calculated for each participant; About two thirds of the participant make less than $US 90 per month. The mean systolic blood pressure was 131.80 ± 30. Eighty (42.3%) participants were overweight with a mean waist circumference of 91.64 ± 11.19 cm. MetS was present in 46 (24.3%). Individuals with MetS were more likely to have increased FRS, = 0.012. One hundred and eighty seven (98.9%) were in the low risk category according to FRS. There was a significant difference in the mean FRS between participants with and without MetS (13.52 10.29 = 0.025); Prevalence of MetS in this study was comparable to the global rate, despite a low economic status. Individuals with MetS were more likely to have cardiovascular disease than persons without MetS, thus emphasizing the need for risk stratification and prompt management.
几位研究人员已证实代谢综合征（MetS）与心血管疾病风险增加有关。弗雷明汉风险评分（FRS）为识别有心血管疾病风险的个体提供了一种简单有效的方法。目的是描述半城市女性队列中代谢综合征的患病率及其与FRS在预测心血管疾病方面的关联；对189名健康女性进行了临床和实验室参数评估。采用国际糖尿病联盟的定义来诊断代谢综合征。为每位参与者计算FRS；约三分之二的参与者每月收入低于90美元。平均收缩压为131.80±30。80名（42.3%）参与者超重，平均腰围为91.64±11.19厘米。46名（24.3%）存在代谢综合征。患有代谢综合征的个体更有可能FRS升高，P = 0.012。根据FRS，187名（98.9%）属于低风险类别。有和没有代谢综合征的参与者之间的平均FRS存在显著差异（13.52对10.29，P = 0.025）；尽管经济状况不佳，但本研究中代谢综合征的患病率与全球患病率相当。患有代谢综合征的个体比没有代谢综合征的个体更有可能患心血管疾病，因此强调了进行风险分层和及时管理的必要性。
