College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, China.
Molecules. 2017 Sep 20;22(9):1580. doi: 10.3390/molecules22091580.
Palladium-catalyzed base-free addition of aryltriolborates to aldehydes has been developed, leading to a wide range of carbinol derivatives in good to excellent yields. The efficiency of this transformation was demonstrated by compatibility with a wide range of functional groups. The present synthetic route to carbinol derivatives could be readily scaled up to gram quantity without difficulty. Thus, this method represents a simple and practical procedure to access carbinol derivatives.
钯催化的芳基三醇硼酸酯与醛的无碱加成反应已经被开发出来，该反应能以良好到优秀的产率得到广泛的仲醇衍生物。这种转化的效率通过与广泛的官能团的兼容性得到了证明。目前合成仲醇衍生物的路线可以很容易地放大到克级而没有困难。因此，这种方法代表了一种简单实用的方法来获得仲醇衍生物。
