Thomas Paul S, Essien Emmanuel E, Ntuk Samuel J, Choudhary Mohammad I
Department of Pharmacognosy and Natural Medicine, University of Uyo, Uyo 520101, Nigeria.
Department of Chemistry, University of Uyo, Uyo 520101, Nigeria.
Medicines (Basel). 2017 Apr 28;4(2):24. doi: 10.3390/medicines4020024.
essential oils from Nigeria were investigated for the first time in order to ascertain their potency as natural antioxidants. is an aromatic and medicinal herb used in ethno-medicine and as a traditional spice for foods. The hydro-distilled oils of were subjected to gas chromatography-mass spectrometry (GC-MS) analysis. Free radical scavenging capacity of the volatile oils was determined using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. Leaf volatile oil contained a high proportion of ()-2-Dodecenal (28.43%), 13-tetradecenal (27.45%), dodecanal (14.59%) and 2,4,5-trimethylbenzaldehyde (10.77%); the stem oil comprised of dodecanal (20.21%), 2,4,5-trimethylbenzaldehyde (18.43%) and ()-2-dodecenal (8.27%), while 2,4,5-trimethylbenzaldehyde (56.08%), 13-tetradecenal (9.26%) and ()-2-dodecenal (7.65%) were the most dominant in the root oil. The IC values for the leaf, stem and root oils were 56 µg/mL, 46µg/mL and 54.5 µg/mL respectively in the DPPH assay while the leaf oil exhibited the highest reducing potential among the test oils in the FRAP assay. The Nigerian volatile oils contain high amount of acyclic aldehydes and aromatic compounds. The oils are a potential source of natural antioxidant as demonstrated by their strong antioxidant activity.
首次对来自尼日利亚的精油进行了研究，以确定其作为天然抗氧化剂的效力。[植物名称]是一种芳香药草，用于民族医学并作为食品的传统香料。[植物名称]的水蒸馏油进行了气相色谱 - 质谱（GC - MS）分析。使用2,2 - 二苯基 - 1 - 苦基肼（DPPH）和铁还原抗氧化能力（FRAP）测定法测定挥发油的自由基清除能力。叶挥发油含有高比例的（） - 2 - 十二碳烯醛（28.43%）、13 - 十四碳烯醛（27.45%）、十二醛（14.59%）和2,4,5 - 三甲基苯甲醛（10.77%）；茎油由十二醛（20.21%）、2,4,5 - 三甲基苯甲醛（18.43%）和（） - 2 - 十二碳烯醛（8.27%）组成，而2,4,5 - 三甲基苯甲醛（56.08%）、13 - 十四碳烯醛（9.26%）和（） - 2 - 十二碳烯醛（7.65%）在根油中占主导地位。在DPPH测定中，叶、茎和根油的IC值分别为56 µg/mL、46µg/mL和54.5 µg/mL，而在FRAP测定中，叶油在测试油中表现出最高的还原潜力。尼日利亚[植物名称]挥发油含有大量的无环醛和芳香族化合物。这些油具有很强的抗氧化活性，是天然抗氧化剂的潜在来源。
