Sah Kunal, Chandra Sunira, Singh Anil, Singh Shweta
Department of Oral Pathology and Microbiology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.
Department of Oral Medicine and Radiology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.
J Oral Maxillofac Pathol. 2017 May-Aug;21(2):321. doi: 10.4103/jomfp.JOMFP_93_16.
Eosinophilic ulcer (EU) is a rare self-limiting chronic benign ulcerative lesion of the oral mucosa often misdiagnosed as oral malignancy. Its etiopathogenesis is ambiguous, but trauma plays an important role in the development. Microscopically, it is characterized by a polymorphic inflammatory infiltrate with a prominent eosinophilic component and large mononuclear cells extending deep into the submucosa, underlying muscle and salivary glands. We discuss a case of EU in a 55-year-old male, which presented with a symptomatic nonhealing ulcer on the right lateral border of the tongue and was further clinically misdiagnosed as malignant ulcer.
嗜酸性溃疡（EU）是一种罕见的口腔黏膜自限性慢性良性溃疡性病变，常被误诊为口腔恶性肿瘤。其发病机制尚不明确，但创伤在其发展过程中起重要作用。在显微镜下，其特征是多形性炎症浸润，伴有突出的嗜酸性成分和大单核细胞，深入黏膜下层、下方肌肉和唾液腺。我们讨论一例55岁男性的嗜酸性溃疡病例，该患者舌右侧缘出现有症状的不愈合溃疡，临床上进一步被误诊为恶性溃疡。
