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表皮囊肿:一项侧重于异常发现的临床病理分析

Epidermal Cysts: A Clinicopathological Analysis with Emphasis on Unusual Findings.

作者信息

Nigam Jitendra Singh, Bharti Jyotsna Naresh, Nair Vivek, Gargade Chitrawati Bal, Deshpande Archana Hemant, Dey Biswajit, Singh Ashok

机构信息

Department of Pathology, Andaman and Nicobar Islands Institute of Medical Sciences, Andaman and Nicobar Islands, India.

出版信息

Int J Trichology. 2017 Jul-Sep;9(3):108-112. doi: 10.4103/ijt.ijt_16_17.

Abstract

BACKGROUND

Epidermoid cysts, one of the common benign intradermal or subcutaneous tumors commonly result from the trauma to the pilosebaceous unit in the hair bearing area. In areas without hair, these cysts are considered implantation and proliferation of squamous epithelium into the dermis due to injury.

AIMS

The aim is to evaluate the clinicopathological details with emphasis on unusual findings related to epidermoid cysts.

STUDY DESIGN

This is a retrospective cross-sectional study carried out over 2 years.

MATERIALS AND METHODS

A total of 103 cases of epidermoid cysts were included in the study. The clinical details such as age, gender, sites, and dimensions were noted. The histopathological findings were evaluated and correlated with the clinical findings.

RESULTS

The highest incidence was observed in the age group of 21-30 years (23.3%, 24/103) and the most common affected region was the head and neck region (32%, 33/103). The size of cysts ranged from 0.3 to 9 cm in diameter with a mean of 2.1 cm. The unusual sites observed in this study were four at the left sole, two at right sole, two at prepuce, and one each at the right finger, left palm, and oral cavity. Histopathological findings included rupture of epidermoid cysts with giant cell reaction, melanin pigmentation, and association with other pathologies such as keloid and lipoma.

CONCLUSION

Epidermoid cysts are common benign intradermal or subcutaneous tumors, but they can have unusual presentations and histopathological findings. Epidermoid cysts need early diagnosis and treatment as they can cause cosmetic and functional impairment.

摘要

背景

表皮样囊肿是常见的良性皮内或皮下肿瘤之一,通常由有毛发区域的毛囊皮脂腺单位受到创伤引起。在无毛区域,这些囊肿被认为是由于损伤导致鳞状上皮植入真皮并增殖。

目的

旨在评估表皮样囊肿的临床病理细节,重点关注与表皮样囊肿相关的不寻常发现。

研究设计

这是一项为期2年的回顾性横断面研究。

材料与方法

本研究共纳入103例表皮样囊肿病例。记录年龄、性别、部位和大小等临床细节。对组织病理学发现进行评估并与临床发现相关联。

结果

最高发病率出现在21 - 30岁年龄组(23.3%,24/103),最常受累区域是头颈部(32%,33/103)。囊肿大小直径范围为0.3至9厘米,平均为2.1厘米。本研究中观察到的不寻常部位有:左足底4例,右足底2例,包皮2例,右手手指、左手掌和口腔各1例。组织病理学发现包括表皮样囊肿破裂伴巨细胞反应、黑色素沉着,以及与瘢痕疙瘩和脂肪瘤等其他病理情况相关。

结论

表皮样囊肿是常见的良性皮内或皮下肿瘤,但它们可能有不寻常的表现和组织病理学发现。表皮样囊肿因可导致美容和功能损害,需要早期诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f71/5596644/ca09abc1798c/IJT-9-108-g001.jpg

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