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神经系统疾病中的畏光现象。

Photophobia in neurologic disorders.

作者信息

Wu Yiwen, Hallett Mark

机构信息

Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive MSC 1428, Building 10, Room 7D37, Bethesda, MD 20892 USA.

出版信息

Transl Neurodegener. 2017 Sep 20;6:26. doi: 10.1186/s40035-017-0095-3. eCollection 2017.

DOI:10.1186/s40035-017-0095-3
PMID:28932391
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5606068/
Abstract

Photophobia is a common symptom seen in many neurologic disorders, however, its pathophysiology remains unclear. Even the term is ambiguous. In this paper, we review the epidemiology and clinical manifestations of photophobia in neurological disorders, including primary headache, blepharospasm, progressive supranuclear palsy, and traumatic brain injury, discuss the definition, etiology and pathogenesis, and summarize practical methods of diagnosis and treatment.

摘要

畏光是许多神经系统疾病中常见的症状,然而,其病理生理学仍不清楚。甚至这个术语也不明确。在本文中,我们回顾了神经系统疾病中畏光的流行病学和临床表现,包括原发性头痛、眼睑痉挛、进行性核上性麻痹和创伤性脑损伤,讨论了定义、病因和发病机制,并总结了实际的诊断和治疗方法。

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1
Photophobia in neurologic disorders.神经系统疾病中的畏光现象。
Transl Neurodegener. 2017 Sep 20;6:26. doi: 10.1186/s40035-017-0095-3. eCollection 2017.
2
Narrative Review of the Pathophysiology of Headaches and Photosensitivity in Mild Traumatic Brain Injury and Concussion.轻度创伤性脑损伤和脑震荡头痛和光敏感性的病理生理学的叙述性综述。
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Photophobia in primary headaches, in essential blepharospasm and in major depression.原发性头痛、特发性眼睑痉挛和重度抑郁症中的畏光现象。
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Shedding light on photophobia.揭示畏光现象。
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Photophobia: When Light Hurts, a Review.畏光:当光明成为痛苦,一篇综述。
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Diagnosis, pathophysiology, and treatment of photophobia.畏光症的诊断、病理生理学及治疗
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Clinical implications of photophobia in progressive supranuclear palsy.进行性核上性麻痹中畏光的临床意义。
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Light-eye-body axis: exploring the network from retinal illumination to systemic regulation.光眼-身体轴:探索从视网膜光照到全身调节的网络。
Theranostics. 2025 Jan 2;15(4):1496-1523. doi: 10.7150/thno.106589. eCollection 2025.
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Photophobia is associated with lower sleep quality in individuals with migraine: results from the American Registry for Migraine Research (ARMR).畏光与偏头痛患者的睡眠质量下降有关:美国偏头痛研究注册中心(ARMR)的研究结果。
J Headache Pain. 2024 Apr 12;25(1):55. doi: 10.1186/s10194-024-01756-9.
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Validation of the Utah Photophobia Symptom Impact Scale (version 2) as a headache-specific photophobia assessment tool.验证犹他畏光症状影响量表(第 2 版)作为一种特定于头痛的畏光评估工具。
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本文引用的文献

1
Clinical implications of the melanopsin-based non-image-forming visual system.基于黑视蛋白的非成像视觉系统的临床意义。
Neurology. 2017 Mar 28;88(13):1282-1290. doi: 10.1212/WNL.0000000000003761. Epub 2017 Mar 1.
2
Diagnosis, pathophysiology, and treatment of photophobia.畏光症的诊断、病理生理学及治疗
Surv Ophthalmol. 2016 Jul-Aug;61(4):466-77. doi: 10.1016/j.survophthal.2016.02.001. Epub 2016 Feb 12.
3
Characterization of Migraineurs Having Allodynia: Results of a Large Population-based Study.患有痛觉过敏的偏头痛患者的特征:一项基于大规模人群研究的结果。
Clin J Pain. 2016 Jul;32(7):631-5. doi: 10.1097/AJP.0000000000000301.
4
Photophobia in primary headaches.原发性头痛中的畏光现象。
Headache. 2015 Apr;55(4):600-4. doi: 10.1111/head.12532. Epub 2015 Mar 19.
5
Onabotulinum toxin a for the treatment of headache in service members with a history of mild traumatic brain injury: a cohort study.用于治疗有轻度创伤性脑损伤病史的军人头痛的A型肉毒毒素:一项队列研究。
Headache. 2015 Mar;55(3):395-406. doi: 10.1111/head.12495. Epub 2015 Feb 3.
6
Photosensitivity in mild traumatic brain injury (mTBI): a retrospective analysis.轻度创伤性脑损伤(mTBI)中的光敏性:一项回顾性分析。
Brain Inj. 2014;28(10):1283-7. doi: 10.3109/02699052.2014.915989. Epub 2014 Jun 19.
7
Prevalence and clinical characteristics of headache in adolescents: a Croatian epidemiological study.青少年头痛的患病率和临床特征:一项克罗地亚的流行病学研究。
Cephalalgia. 2014 Apr;34(4):289-97. doi: 10.1177/0333102413507636. Epub 2013 Oct 14.
8
Unanswered questions in headache: so what is photophobia, anyway?头痛未解之谜:那么,畏光是怎么回事?
Headache. 2013 Nov-Dec;53(10):1673-4. doi: 10.1111/head.12227. Epub 2013 Sep 23.
9
The International Classification of Headache Disorders, 3rd edition (beta version).《国际头痛疾病分类》第三版(试用版)
Cephalalgia. 2013 Jul;33(9):629-808. doi: 10.1177/0333102413485658.
10
Central sensitization in photophobic and non-photophobic migraineurs: possible role of retino nuclear way in the central sensitization process.畏光和非畏光偏头痛患者的中枢敏化:视核通路在中枢敏化过程中的可能作用。
Neurol Sci. 2013 May;34 Suppl 1:S133-5. doi: 10.1007/s10072-013-1369-x.