Ahn Sangwoo, Chen Yan, Bredow Tim, Cheung Corjena, Yu Fang
University of Minnesota School of Nursing, Minneapolis, Minnesota.
Taihe Hospital, Hubei Province, China.
J Parkinsons Dis Alzheimers Dis. 2017 Apr;4(1). doi: 10.13188/2376-922X.1000021. Epub 2017 Apr 20.
Parkinson's disease is a neurodegenerative chronic condition with a declining trajectory and lack of a cure, making quality of life an important aspect of care. The purpose of this literature review was to analyze the state-of-the-science on the effects of non-pharmacological treatments on quality of life in person's with Parkinson's disease. Literature search was conducted using keywords in electronic databases up to September 1, 2016 and cross-searching the references of identified articles. Of the 259 articles generated, 26 met the eligibility criteria and were included in this review. The majority of studies (77%) were Level I evidence and 23% Level II evidence. The levels of study quality were: strong (50%), moderate (15%), and weak (35%). The interventions varied across studies with 15 studies evaluating a similar intervention. About 58% of the studies showed that the interventions improved quality of life. In conclusion, a variety of non-pharmacological interventions have been increasingly studied for their effects on quality of life in Parkinson's disease, showing initial promising results. However, most interventions were only examined by a limited number of studies and the minimal and optimal intervention doses needed for improving quality of life are yet unknown.
帕金森病是一种神经退行性慢性疾病，病情呈逐渐恶化趋势且无法治愈，因此生活质量成为护理的一个重要方面。这篇文献综述的目的是分析非药物治疗对帕金森病患者生活质量影响的科学现状。通过在电子数据库中使用关键词进行文献检索，检索截至2016年9月1日的文献，并对已识别文章的参考文献进行交叉检索。在生成的259篇文章中，26篇符合纳入标准并被纳入本综述。大多数研究（77%）为一级证据，23%为二级证据。研究质量水平为：强（50%）、中（15%）、弱（35%）。不同研究中的干预措施各不相同，有15项研究评估了类似的干预措施。约58%的研究表明这些干预措施改善了生活质量。总之，越来越多的研究探讨了各种非药物干预措施对帕金森病患者生活质量的影响，并显示出初步的良好结果。然而，大多数干预措施仅在少数研究中得到检验，改善生活质量所需的最小和最佳干预剂量尚不清楚。
