Kim Dong Wook
Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, 75, Bokji-ro, Busanjin-gu, Busan, 47392, South Korea.
Radiol Med. 2018 Jan;123(1):20-27. doi: 10.1007/s11547-017-0815-x. Epub 2017 Sep 20.
No previous study has investigated computed tomography (CT) features of the major salivary glands (MSGs) after postoperative radioactive iodine ablation (RIA). This study aimed to assess CT features of the MSGs after RIA in patients with papillary thyroid carcinoma (PTC).
The study population comprised consecutively registered PTC patients who had undergone total thyroidectomy, RIA, follow-up neck ultrasonography (US), and neck CT. The US and CT features of the parotid and submandibular glands in each patient were retrospectively evaluated by a single radiologist. Post-RIA changes were determined by comparisons between follow-up neck US results (main reference) and between preoperative and post-RIA neck CT features.
Of the 28 patients, 13 (46.4%) showed post-RIA changes in the parotid glands (n = 8), submandibular glands (n = 0), or both (n = 5) on neck CT. Of the 56 MSGs in 28 patients, post-RIA changes were more common in the parotid glands (n = 23, 41.1%) than in the submandibular glands (n = 8, 14.3%). The common CT findings of post-RIA changes in the parotid gland included low parenchymal attenuation, decreased glandular size, a lobulated margin, decreased or increased parenchymal enhancement, and an inhomogeneous enhancement pattern, whereas common CT findings of post-RIA changes in the submandibular gland included decreased glandular size, a lobulated margin, iso-enhancement, and an inhomogeneous enhancement pattern.
The common CT features of post-RIA changes in MSGs include decreased glandular size, a lobulated margin, and an inhomogeneous enhancement pattern.
既往尚无研究调查术后放射性碘消融（RIA）后大唾液腺（MSG）的计算机断层扫描（CT）特征。本研究旨在评估甲状腺乳头状癌（PTC）患者RIA后MSG的CT特征。
研究人群包括连续登记的接受全甲状腺切除术、RIA、随访颈部超声（US）和颈部CT的PTC患者。由一名放射科医生对每位患者腮腺和颌下腺的US和CT特征进行回顾性评估。通过随访颈部US结果之间的比较（主要参考）以及术前和RIA后颈部CT特征之间的比较来确定RIA后的变化。
28例患者中，13例（46.4%）颈部CT显示腮腺（n = 8）、颌下腺（n = 0）或两者（n = 5）出现RIA后变化。28例患者的56个MSG中，RIA后变化在腮腺（n = 23，41.1%）比在颌下腺（n = 8，14.3%）更常见。腮腺RIA后变化的常见CT表现包括实质低密度、腺体大小减小、边缘分叶、实质强化降低或增加以及强化不均匀，而颌下腺RIA后变化的常见CT表现包括腺体大小减小、边缘分叶、等强化和强化不均匀。
MSG RIA后变化的常见CT特征包括腺体大小减小、边缘分叶和强化不均匀。
