Zhang Fang, Guo Sheng, Qian Da-Wei, Zhang Xia, Yang Xiao-Chun, Li Yong-Jing, Duan Jin-Ao
School of Pharmacy, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, State Administration of Traditional Chinese Medicine Key Laboratory of Chinese Medicinal Resouces Recycling Utilization, Nanjing University of Chinese Medicine, Nanjing 210023, China.
School of Pharmacy, Ningxia Medical University, Yinchuan 750021, China.
Zhongguo Zhong Yao Za Zhi. 2016 Dec;41(23):4285-4291. doi: 10.4268/cjcmm20162301.
Lycii Fructus is a traditional medicinal and edible herb, with the function of liver and kidney nourishing, blood and eyesight replenishing. As the most important active substance in the fruits of Lycium barbarum, Lycium barbarum polysaccharides (LBP) have been demonstrated to play multiple pharmacological activities, with broad prospects for development and utilization. Based on the comprehensive deep analysis of global LBP patent output, the current patent LBP features were explored from the perspective of development trend, technology field distribution, time dimension, technology life curve and patent applicant. The development trend of Chinese LBP industry was also revealed. At present, the research and development of LBP is in the "development period", with a good development track in which the main research institutions remain domestic ones. At the same time, problem still presents in the lack of industrialization, which means that the advantage of natural resources has not been transformed into industrial advantages of LBP. The format of potential product group and prospect of LBP were also analyzed to provide scientific information for the effective development,comprehensive utilization and collaborative innovation mechanism of Chinese Lycium barbarum resources and LBP.
枸杞子是一种传统的药食两用草本植物,具有滋补肝肾、补血明目之功效。枸杞多糖(LBP)作为宁夏枸杞果实中最重要的活性物质,已被证明具有多种药理活性,具有广阔的开发利用前景。通过对全球枸杞多糖专利产出的全面深入分析,从发展趋势、技术领域分布、时间维度、技术生命周期曲线和专利申请人等角度探讨了当前专利枸杞多糖的特征。同时揭示了我国枸杞多糖产业的发展趋势。目前,枸杞多糖的研发处于“发展期”,发展轨迹良好,主要研究机构仍在国内。但同时也存在产业化不足的问题,即自然资源优势尚未转化为枸杞多糖的产业优势。分析了枸杞多糖潜在产品组的形式和前景,为我国枸杞资源和枸杞多糖的有效开发、综合利用及协同创新机制提供科学依据。