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儿茶素对心血管的保护作用概述

An Overview on Cardiovascular Protective Effects of Catechins.

作者信息

Shaterzadeh-Yazdi Hanieh, Farkhondeh Tahereh, Samarghandian Saeed

机构信息

Research Center of Pardis Hospital, Mashhad, Iran.

Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.

出版信息

Cardiovasc Hematol Disord Drug Targets. 2017;17(3):154-160. doi: 10.2174/1871529X17666170921115735.

DOI:10.2174/1871529X17666170921115735
PMID:28933274
Abstract

BACKGROUND

The impact of diet strategies to manage cardiovascular disease has been focused in recent years. The food ingredients, such as flavonoids, are known as cardioprotective agents; however, it is not fully understood how these compounds are effective against cardiovascular problems. Catechins are polyphenolic compounds exhibiting several biological activities in the human body, potentially in the treatment of cardiovascular disease. The present study indicates that catechins may be effective against cardiovascular problems through modulating blood lipid metabolism, protecting vascular endothelial, and decreasing blood pressure.

CONCLUSION

The current review has evaluated various studies on the role of catechins in the prevention and treatment of cardiovascular disorders by focusing on oxidative stress and inflammatory responses.

摘要

背景

近年来,饮食策略对心血管疾病管理的影响一直是关注焦点。黄酮类等食物成分被认为是心脏保护剂;然而,这些化合物如何有效对抗心血管问题尚未完全明确。儿茶素是在人体中具有多种生物活性的多酚类化合物,可能对心血管疾病有治疗作用。本研究表明,儿茶素可能通过调节血脂代谢、保护血管内皮和降低血压来有效对抗心血管问题。

结论

本综述通过关注氧化应激和炎症反应,评估了儿茶素在预防和治疗心血管疾病方面作用的各种研究。

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