• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

穴位激活:微循环中的反应及肥大细胞的作用

Acupoint Activation: Response in Microcirculation and the Role of Mast Cells.

作者信息

Wang Guangjun, Litscher Daniela, Tian Yuying, Gaischek Ingrid, Jia Shuyong, Wang Lu, Zhang Weibo, Litscher Gerhard

机构信息

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie, Dongzhimennei, Beijing 100700, China.

Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine, and TCM Research Center Graz, Medical University of Graz, Auenbruggerplatz 29, Graz 8036, Austria.

出版信息

Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056.

DOI:10.3390/medicines1010056
PMID:28933377
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5532981/
Abstract

BACKGROUND

According to Traditional Chinese Medicine (TCM) theory, acupuncture effects are based on the integrity function of meridians. Meridians are thought to regulate body function through the normal flow of qi and/or blood. Disturbances in this flow are thought to cause disease, and acupuncture techniques are believed to cure disease by regulating this flow. However, it is still difficult to understand the exact meaning of qi and to evaluate the activation of meridians. Thus, more and more attention has been focused on the relationship of acupuncture and circulation.

METHODS

In this narrative review, the authors focus on the state of the art in acupoint activation, microcirculation response, and on investigation of mast cells, based on current literature research.

RESULTS

Altogether, 52 references are cited and discussed critically. A schematic diagram of the relationship between acupuncture stimulation, changes of microcirculation and mast cells is presented as result.

CONCLUSION

The block diagram presented in this review article shows that mast cells might play an important role in circulation response after acupoint stimulation.

摘要

背景

根据中医理论,针刺效应基于经络的完整功能。经络被认为通过气和/或血的正常运行来调节身体功能。这种运行的紊乱被认为会导致疾病,而针刺技术被认为通过调节这种运行来治愈疾病。然而,仍然难以理解气的确切含义以及评估经络的激活情况。因此,越来越多的关注集中在针刺与循环的关系上。

方法

在这篇叙述性综述中,作者基于当前的文献研究,重点关注穴位激活、微循环反应以及肥大细胞研究的现状。

结果

共引用并批判性地讨论了52篇参考文献。结果呈现了针刺刺激、微循环变化和肥大细胞之间关系的示意图。

结论

这篇综述文章中呈现的框图表明,肥大细胞可能在穴位刺激后的循环反应中发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeb8/5532981/4049b6f7a454/medicines-01-00056-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeb8/5532981/4049b6f7a454/medicines-01-00056-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eeb8/5532981/4049b6f7a454/medicines-01-00056-g001.jpg

相似文献

1
Acupoint Activation: Response in Microcirculation and the Role of Mast Cells.穴位激活:微循环中的反应及肥大细胞的作用
Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056.
2
['s theory on mast cells and meridian-acupoint and its research prospect].肥大细胞与经络腧穴理论及其研究展望
Zhongguo Zhen Jiu. 2016 Oct 12;36(10):1063-1068. doi: 10.13703/j.0255-2930.2016.10.016.
3
[Development on research of acupuncture effects on microcirculation].
Zhongguo Zhen Jiu. 2015 Feb;35(2):203-8.
4
[Analysis on characteristics of meridians and acupoints of acupuncture and moxibustion for diarrhea in ancient based on data mining].基于数据挖掘的古代艾灸治疗腹泻的经络腧穴特点分析
Zhongguo Zhen Jiu. 2013 Oct;33(10):905-9.
5
[Amplification effect of acupoint from feeling of acupoint and transmitting of meridian].[从穴位感觉与经络传导看穴位的放大效应]
Zhongguo Zhen Jiu. 2013 Oct;33(10):910-2.
6
[Acupoint selection for acute migraine treated with acupuncture].[针刺治疗急性偏头痛的选穴]
Zhongguo Zhen Jiu. 2018 Nov 12;38(11):1183-8. doi: 10.13703/j.0255-2930.2018.11.013.
7
[Analysis on the acupoint conception].
Zhongguo Zhen Jiu. 2017 Feb 12;37(2):149-152. doi: 10.13703/j.0255-2930.2017.02.011.
8
[Acupoint selection for acupuncture analgesia based on the relationship of "the opening-closing- pivoting theory" with meridians and organs].基于“开合枢理论”与经络脏腑关系的针刺镇痛选穴[研究]
Zhongguo Zhen Jiu. 2018 May 12;38(5):5353-8. doi: 10.13703/j.0255-2930.2018.05.022.
9
[Discussion of relation between acupuncture methods and the directions of qi in meridians].[针灸方法与经络之气运行方向的关系探讨]
Zhongguo Zhen Jiu. 2011 Sep;31(9):846-9.
10
[Mechanism and medical model formation of meridians in circulating qi and blood].[经络气血运行的机制与医学模型形成]
Zhongguo Zhen Jiu. 2010 Apr;30(4):296-300.

引用本文的文献

1
Biological effect of acupuncture on peripheral facial paralysis.针刺治疗周围性面瘫的生物学效应。
Front Neurol. 2025 Apr 24;16:1516904. doi: 10.3389/fneur.2025.1516904. eCollection 2025.
2
Can acupuncture increase microcirculation in peripheral artery disease and diabetic foot syndrome? - a pilot study.针刺能否增加外周动脉疾病和糖尿病足综合征的微循环?——一项初步研究。
Front Med (Lausanne). 2024 Feb 27;11:1371056. doi: 10.3389/fmed.2024.1371056. eCollection 2024.
3
Effect of Low- and High-Frequency Auricular Stimulation with Electro-Acupuncture on Cutaneous Microcirculation: A Cross-Over Study in Healthy Subjects.

本文引用的文献

1
Mast cell-nerve cell interaction at acupoint: modeling mechanotransduction pathway induced by acupuncture.穴位处肥大细胞与神经细胞的相互作用:针刺诱导机械转导通路的建模
Int J Biol Sci. 2014 Apr 26;10(5):511-9. doi: 10.7150/ijbs.8631. eCollection 2014.
2
Somatosensory Nerve Fibers Mediated Generation of De-qi in Manual Acupuncture and Local Moxibustion-Like Stimuli-Modulated Gastric Motility in Rats.躯体感觉神经纤维介导的手动针刺和局部类似艾灸刺激调节大鼠胃动力产生的“得气”。
Evid Based Complement Alternat Med. 2014;2014:673239. doi: 10.1155/2014/673239. Epub 2014 Apr 30.
3
Acupuncture De-qi: From Characterization to Underlying Mechanism.
低频和高频耳针电刺激对皮肤微循环的影响:一项针对健康受试者的交叉研究。
Medicines (Basel). 2023 Feb 13;10(2):17. doi: 10.3390/medicines10020017.
4
The effects of laser acupuncture on the modulation of cartilage extracellular matrix macromolecules in rats with adjuvant-induced arthritis.激光针灸对佐剂性关节炎大鼠软骨细胞外基质大分子的调节作用。
PLoS One. 2019 Mar 18;14(3):e0211341. doi: 10.1371/journal.pone.0211341. eCollection 2019.
5
Laser Speckle Imaging of Sensitized Acupoints.致敏穴位的激光散斑成像
Evid Based Complement Alternat Med. 2018 Jul 17;2018:7308767. doi: 10.1155/2018/7308767. eCollection 2018.
6
Exploring the Relationship between Blood Flux Signals and HRV following Different Thermal Stimulations using Complexity Analysis.采用复杂性分析方法探索不同热刺激下血流信号与 HRV 之间的关系。
Sci Rep. 2018 Jun 12;8(1):8982. doi: 10.1038/s41598-018-27374-5.
7
Mast cells are important regulator of acupoint sensitization via the secretion of tryptase, 5-hydroxytryptamine, and histamine.肥大细胞通过分泌类胰蛋白酶、5-羟色胺和组胺,是穴位敏化的重要调节因子。
PLoS One. 2018 Mar 7;13(3):e0194022. doi: 10.1371/journal.pone.0194022. eCollection 2018.
8
Sino-Austrian High-Tech Acupuncture Network-Annual Report 2014.中奥高科技针灸网络——2014年度报告
Medicines (Basel). 2014 Dec 24;2(1):1-10. doi: 10.3390/medicines2010001.
针刺得气:从特征描述到潜在机制。
Evid Based Complement Alternat Med. 2013;2013:518784. doi: 10.1155/2013/518784. Epub 2013 Sep 8.
4
Study on the dynamic compound structure composed of mast cells, blood vessels, and nerves in rat acupoint.大鼠穴位中肥大细胞、血管和神经的动态复合结构研究。
Evid Based Complement Alternat Med. 2013;2013:160651. doi: 10.1155/2013/160651. Epub 2013 Jun 26.
5
[Relationship between regional mast cell activity and peripheral nerve discharges during manual acupuncture stimulation of "Zusanli" (ST 36)].[手针刺激“足三里”(ST 36)时局部肥大细胞活性与外周神经放电的关系]
Zhen Ci Yan Jiu. 2013 Apr;38(2):118-22.
6
To be or not to be: the needling sensation (de qi) in acupuncture.存在还是不存在:针刺中的针感(得气)。
Acupunct Med. 2013 Jun;31(2):129-31. doi: 10.1136/acupmed-2013-010384.
7
Understanding propagated sensation along meridians by volume transmission in peripheral tissue.理解外周组织容积传递中的经络循行感觉。
Chin J Integr Med. 2013 May;19(5):330-9. doi: 10.1007/s11655-013-1456-0. Epub 2013 May 15.
8
The influence of skin microcirculation blood perfusion at zusanli acupoint by stimulating with lift-thrust reinforcing and reducing acupuncture manipulation methods on healthy adults.提插补泻手法刺激足三里穴对健康成年人皮肤微循环血流灌注的影响。
Evid Based Complement Alternat Med. 2013;2013:452697. doi: 10.1155/2013/452697. Epub 2013 Mar 12.
9
Physiological changes associated with de qi during electroacupuncture to LI4 and LI11: a randomised, placebo-controlled trial.针刺 LI4 和 LI11 时与得气相关的生理变化:一项随机、安慰剂对照试验。
Acupunct Med. 2013 Jun;31(2):143-50. doi: 10.1136/acupmed-2012-010280. Epub 2013 Mar 30.
10
A literature review of de qi in clinical studies.临床研究中“得气”的文献综述。
Acupunct Med. 2013 Jun;31(2):132-42. doi: 10.1136/acupmed-2012-010279. Epub 2013 Mar 13.