Muhanna Rawan G, Aljuraiban Ghadeer S, Almadani Najwa K, Alquraishi Mohammed, El-Sharkawy Mohamed S, Abulmeaty Mahmoud M A
Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh P.O. Box 11362, Saudi Arabia.
Department of Radiology and Medical Imaging, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh P.O. Box 11922, Saudi Arabia.
Healthcare (Basel). 2022 Feb 23;10(3):419. doi: 10.3390/healthcare10030419.
The use of bioelectrical impedance analysis (BIA) in clinical settings is common. However, the value of BIA-based parameters in diagnosing metabolic syndrome (MetS) in children is under-investigated. Herein, we aimed to study the usefulness of BIA-indices in the diagnoses of MetS in 6-10-year-old girls. Therefore, a diagnostic accuracy case-control study was conducted, which included 75 girls aged 10-16 years, divided into three age-matched groups (normal, None-MetS, and MetS). Anthropometric indices, BIA parameters (including fat-free mass (FFM), body fat percent (BFP), and total body water (TBW)), blood pressure (BP), and blood samples were collected. Our main findings show that for girls in None-MetS and MetS groups, the waist circumference (WC) correlated positively with waist-hip ratio and mid-arm circumference (r = 0.58, 0.47, respectively), but not with BFP based on skinfold thickness (SFT), or mid-arm muscle area. WC was positively correlated with FFM and TBW, while high-density lipoprotein was inversely correlated with FFM. However, fasting blood glucose, triglycerides and BP showed no association with anthropometric measurements and BIA components. WC was the best indicator of MetS (AUC = 0.88, cut-off = 81.5 cm), followed by BMI (AUC = 0.84, cut-off = 26.9 kg/m), while BFP based on SFT was the least sensitive (62.5%). In conclusion, apart from the FM index, anthropometric parameters such as WC are more valuable in diagnosing MetS in young adolescent girls.
生物电阻抗分析（BIA）在临床环境中的应用很常见。然而，基于BIA的参数在诊断儿童代谢综合征（MetS）方面的价值尚未得到充分研究。在此，我们旨在研究BIA指标在诊断6至10岁女孩MetS中的有用性。因此，我们进行了一项诊断准确性的病例对照研究，该研究纳入了75名10至16岁的女孩，分为三个年龄匹配的组（正常组、非MetS组和MetS组）。收集了人体测量指标、BIA参数（包括去脂体重（FFM）、体脂百分比（BFP）和总体水（TBW））、血压（BP）和血液样本。我们的主要研究结果表明，对于非MetS组和MetS组的女孩，腰围（WC）与腰臀比和上臂围呈正相关（分别为r = 0.58和0.47），但与基于皮褶厚度（SFT）的BFP或上臂肌肉面积无关。WC与FFM和TBW呈正相关，而高密度脂蛋白与FFM呈负相关。然而，空腹血糖、甘油三酯和BP与人体测量指标和BIA成分无关联。WC是MetS的最佳指标（AUC = 0.88，临界值 = 81.5 cm），其次是BMI（AUC = 0.84，临界值 = 26.9 kg/m），而基于SFT的BFP最不敏感（62.5%）。总之，除了FM指数外，诸如WC等人体测量参数在诊断年轻青春期女孩的MetS方面更有价值。
