a Key Laboratory of Modern Acoustics (MOE), Department of Physics , Collaborative Innovation Center of Advanced Microstructure, Nanjing University , Nanjing , China.
b Department of Ultrasonography , the Affiliated Hospital of Nanjing University of Chinese Medicine , Nanjing , China.
Comput Assist Surg (Abingdon). 2017 Dec;22(sup1):93-99. doi: 10.1080/24699322.2017.1379229. Epub 2017 Sep 22.
4-Dimensional hysterosalpingo-contrast sonography (4 D HyCoSy) using SonoVue is regarded as a really good option available for evaluating fallopian tubal patency. This study was designed to assess the pain and adverse effects incurred by women undergoing 4 D HyCoSy. Through evaluating the pelvic pain immediately after 4 D HyCoSy and 30 min after 4 D HyCoSy, the circumstances of the pain relief was also observed. The predictive factors of pain were assessed simultaneously. 827 consecutive women as part of infertility evaluation were included. The pain experienced was then assessed on a 10-cm visual analogue scale (VAS). Each patient was questioned to rate the pain at two different points of time (T1, immediately after 4 D HyCoSy; T2, 30 min after 4 D HyCoSy). 818/827 (98.9%) patients completed the procedure. Pain was experienced by 757/818 (92.5%) of subjects. 30 min after HyCoSy procedure, only 0.5% (4/818) patients feel severe pelvic pain and after 15-30 minutes of rest, these patients were relieved of pain. Age, cycle length, duration of menses, and duration of infertility were not significantly correlated with pain associated with 4 D HyCoSy as assessed by VAS. Women with tubal obstruction experienced a significant increase in 4 D HyCoSy-associated pain. There were significant differences in the degree of pain between different tubal patency (p <0.01). Overall, 4 D HyCoSy, a user-friendly, multidimensional technology, has the advantage of real-time, dynamic, well tolerated, and low serious complications, which make it a good way for evaluating fallopian tubal patency. The technique aids in making choices concerning further procedures for the diagnosis and treatment of infertility. Most of women experience pain associated with the procedure and 30 minute period of observation is useful.
四维子宫输卵管超声造影（4D HyCoSy）联合声诺维被认为是评估输卵管通畅性的一种较好的选择。本研究旨在评估行 4D HyCoSy 术的患者的疼痛和不良反应。通过评估 4D HyCoSy 术后即刻和 30 分钟后盆腔疼痛的情况，观察疼痛缓解情况。同时评估疼痛的预测因素。将 827 例连续接受不孕症评估的患者纳入本研究。采用 10cm 视觉模拟评分（VAS）评估疼痛程度。在两个不同时间点（T1，4D HyCoSy 术后即刻；T2，4D HyCoSy 术后 30 分钟）询问每位患者的疼痛程度。818/827（98.9%）例患者完成了该过程。757/818（92.5%）例患者有疼痛。HyCoSy 术后 30 分钟，仅 0.5%（4/818）例患者感觉严重盆腔疼痛，休息 15-30 分钟后疼痛缓解。年龄、周期长度、经期持续时间和不孕持续时间与 VAS 评估的 4D HyCoSy 相关疼痛无显著相关性。输卵管阻塞的患者在 4D HyCoSy 相关疼痛方面显著增加。不同输卵管通畅程度之间疼痛程度存在显著差异（p<0.01）。总的来说，4D HyCoSy 是一种用户友好、多维的技术，具有实时、动态、耐受性好、严重并发症少的优点，是评估输卵管通畅性的一种较好的方法。该技术有助于选择进一步的诊断和治疗不孕的方法。大多数女性在接受该检查时会感到疼痛，而 30 分钟的观察期是有用的。
