Department of Neurological Surgery, Rush University Medical Center, Chicago, Illinois, USA.
Department of Neurosurgery, Wakayama Medical University, Wakayama City, Japan.
J Neurointerv Surg. 2018 Mar;10(3):274-278. doi: 10.1136/neurintsurg-2017-013074. Epub 2017 Sep 22.
The aim of this study is to demonstrate the differences between the new Low-profile Visualized Intraluminal Support (LVIS Blue) stenting device and the Flow Redirection Endoluminal Device (FRED) using a series of bench-top evaluations and optical coherence tomography (OCT) images in a cadaveric preparation of the basilar artery.
The first part of the evaluation was bench-top microscopic documentation of metal coverage for LVIS Blue and FRED stents. OCT images of the cerebral vessels and deployed stents were acquired using OCT intravascular imaging. The stents were deployed from the left posterior cerebral artery to the basilar artery in a fresh frozen cadaver. Wall apposition and the relationship to jailed perforators were evaluated.
The metal coverage along the inner curves of the LVIS Blue stent was similar to that along the outer curves of the FRED stent. The LVIS Blue stent cell size was compatible for crossing with the tested microcatheters after deployment of the stent. The LVIS Blue stent showed better wall apposition and less coverage of the perforator than the FRED stent in the cadaver experiment.
LVIS Blue has a good crossing profile for microcatheters, better wall apposition, and less perforator coverage than FRED. These are desirable features in territories with high densities of perforators such as the posterior circulation.
本研究旨在通过基底动脉尸体标本的一系列台架评估和光学相干断层扫描（OCT）图像，展示新型低轮廓可视化腔内支撑（LVIS Blue）支架与血流转向腔内装置（FRED）之间的差异。
评估的第一部分是对 LVIS Blue 和 FRED 支架的金属覆盖率进行台架显微镜记录。使用 OCT 血管内成像获取脑血管和展开支架的 OCT 图像。支架从左大脑后动脉部署到基底动脉，在新鲜冷冻的尸体中进行。评估壁贴附和与受困穿支动脉的关系。
LVIS Blue 支架内曲线的金属覆盖率与 FRED 支架外曲线的金属覆盖率相似。LVIS Blue 支架展开后，其支架细胞尺寸与测试微导管兼容，可穿过微导管。在尸体实验中，与 FRED 支架相比，LVIS Blue 支架具有更好的贴壁和更少的穿支动脉覆盖。
与 FRED 相比，LVIS Blue 具有良好的微导管穿越特性、更好的贴壁效果和更少的穿支动脉覆盖。这些是在穿支动脉密度较高的区域（如后循环）所期望的特性。
