Pettigrew J D, Dreher B
National Vision Research Institute of Australia, Carlton.
Proc R Soc Lond B Biol Sci. 1987 Dec 22;232(1268):297-321. doi: 10.1098/rspb.1987.0076.
In the cat, parallel streams of information processing have been traced from X-, Y- and W-type retinal ganglion cells to visual cortical areas 17 (X-, Y- and W-type), 18 (Y-type) and 19 (W-type). In the present study we have examined, in the anaesthetized and paralysed adult cat, the role played by X-, Y- and W-subsystems, projecting to areas 17 and 19, in the processing of binocular retinal disparity. The tapetal reflection technique was used to monitor residual eye movements and to provide a map, for each eye, of the retinal blood vessels which could later be compared with retinal wholemounts stained with cresyl violet to reveal the area centralis. The receptive-field disparities of cells recorded from areas 17 and 19 were compared with each other and with reference to the visual axes defined by the area centralis of each eye. Cells of area 19 (receiving W-type input) had horizontal receptive-field disparities that were significantly more divergent than those of the cells in area 17 and 17-18 'border region'. Referred to the area centralis, the mean horizontal receptive-field disparity in area 19 was -0.5 degrees (+/- 0.8 degrees). The mean horizontal receptive-field disparity of area 17 (receiving X-, Y- and W-type input) was convergent with respect to the visual axis at +2 degrees (+/- 0.5 degrees). Finally, the mean horizontal receptive-field disparity of the cells in the 17-18 border region (which receive mainly Y-type input) was even more convergent (2.6 degrees +/- 1.5 degrees) than that of area 17. Binocular interactions of cortical neurons were tested with the Risley biprism technique. Area 19 cells had maximal responses to binocular stimulation when the receptive-field disparities were either close to zero or slightly divergent. In contrast, area 17 cells tended to respond optimally to disparities that were either slightly or strongly convergent. At the level of the lateral geniculate nucleus there were significant differences between the receptive-field disparities inferred from the comparison of receptive-field positions of adjacent neurons recorded on either side of the border between the A and A1 geniculate laminae and those inferred from a similar comparison at the C1-C2 border. The mean horizontal disparities inferred from the interlaminar comparison at the A-A1 border were +2.1 degrees (+/- 0.3 degrees); those inferred from the interlaminar comparison at the C1-C2 border -0.2 (+/- 0.2 degrees) were more divergent.(ABSTRACT TRUNCATED AT 400 WORDS)
在猫中，已追踪到从X型、Y型和W型视网膜神经节细胞到视觉皮层17区（X型、Y型和W型）、18区（Y型）和19区（W型）的平行信息流。在本研究中，我们在麻醉并麻痹的成年猫身上，研究了投射到17区和19区的X型、Y型和W型子系统在双眼视网膜视差处理中的作用。使用绒毡层反射技术监测残余眼动，并为每只眼睛提供视网膜血管图，之后可将其与用甲酚紫染色的视网膜全层标本进行比较，以显示中央凹。将从17区和19区记录的细胞的感受野视差相互比较，并参照每只眼睛中央凹所定义的视轴。19区的细胞（接受W型输入）具有水平感受野视差，其发散程度明显大于17区和17 - 18区“边界区域”细胞的视差。以中央凹为参照，19区的平均水平感受野视差为 -0.5度（±0.8度）。17区（接受X型、Y型和W型输入）的平均水平感受野视差相对于视轴在 +2度（±0.5度）处呈会聚状态。最后，17 - 18区边界区域（主要接受Y型输入）细胞的平均水平感受野视差（2.6度±1.5度）比17区的更会聚。用里斯利双棱镜技术测试了皮层神经元的双眼相互作用。当感受野视差接近零或略有发散时，19区细胞对双眼刺激有最大反应。相比之下，17区细胞往往对略有会聚或强烈会聚的视差反应最佳。在外侧膝状体核水平，从A层和A1层之间边界两侧记录的相邻神经元的感受野位置比较中推断出的感受野视差，与在C1 - C2边界进行类似比较所推断出的感受野视差之间存在显著差异。从A - A1边界的层间比较推断出的平均水平视差为 +2.1度（±0.3度）；从C1 - C2边界的层间比较推断出的平均水平视差为 -0.2度（±0.2度），其发散程度更大。（摘要截选至400字）
