Gupta Kartik, Jha Milind, Jadon Ranveer S, Sood Rita
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.
BMJ Case Rep. 2017 Sep 23;2017:bcr-2017-220802. doi: 10.1136/bcr-2017-220802.
We report a case of a young man who allegedly consumed 100 mL of an indigenous pesticide which is used for the killing of rats in households in India. The constituents were azadirachtin oil (40%), tea oil (15%), pine oil (25%) and kerosene oil (20%). He presented to us with shortness of breath and altered sensorium and was found to have fMetHb (fraction of methaemoglobin) level of 80%, which has been postulated to have a fatal outcome. He responded to a low dose of methylene blue along with intravenous vitamin C and the level of fMetHb came down to 20% within 1 hour. His sensorium improved markedly with a decrease in fMetHb to non-toxic levels and he was discharged 5 days after admission. A literature review pertaining to these constituents individually or in combination causing methaemoglobinaemia is discussed in the context of this case.
我们报告了一例年轻男性病例,据称他摄入了100毫升印度家庭用于灭鼠的一种本土杀虫剂。其成分包括印楝素油(40%)、茶油(15%)、松油(25%)和煤油(20%)。他因呼吸急促和意识改变前来就诊,发现其高铁血红蛋白(fMetHb)水平为80%,据推测这可能会导致致命后果。他对低剂量亚甲蓝联合静脉注射维生素C有反应,fMetHb水平在1小时内降至20%。随着fMetHb降至无毒水平,他的意识明显改善,入院5天后出院。结合该病例讨论了关于这些成分单独或联合导致高铁血红蛋白血症的文献综述。