Akizue Naoki, Suzuki Eiichiro, Yokoyama Masayuki, Inoue Masanori, Wakamatsu Toru, Saito Tomoko, Kusakabe Yuko, Ogasawara Sadahisa, Ooka Yoshihiko, Tawada Akinobu, Maru Yugo, Matsue Hiroyuki, Chiba Tetsuhiro
Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Japan.
Department of Dermatology, Graduate School of Medicine, Chiba University, Japan.
Intern Med. 2017 Nov 15;56(22):3041-3045. doi: 10.2169/internalmedicine.8885-17. Epub 2017 Sep 25.
Although Henoch-Schönlein purpura (HSP) is known to be accompanied by malignancies, cases with hepatobiliary cancer are extremely rare. A 62-year-old man with palpable purpura rapidly extending to both lower legs was admitted to our hospital. He was undergoing follow-up for cirrhosis caused by chronic hepatitis B virus infection and hepatocellular carcinoma (HCC). He had renal dysfunction with hematuria and proteinuria and abdominal pain. Based on the clinical presentation and skin biopsy findings, he was diagnosed with HSP. The administration of steroids resulted in the rapid improvement of the patient's symptoms and he was discharged 12 days after admission.
虽然已知过敏性紫癜（HSP）会伴有恶性肿瘤，但合并肝胆癌的病例极为罕见。一名62岁男性因双下肢迅速出现可触及的紫癜入住我院。他因慢性乙型肝炎病毒感染导致的肝硬化和肝细胞癌（HCC）正在接受随访。他有肾功能不全伴血尿、蛋白尿和腹痛。根据临床表现和皮肤活检结果，他被诊断为HSP。使用类固醇治疗后患者症状迅速改善，入院12天后出院。
